Abstract Objectives Although the ISPOR Value of Information (VOI) Task Force's reports
outline VOI concepts and provide good-practice recommendations, there is no guidance for …

Objective This sco** review sought to map the breadth of literature on the use of adaptive
design trials in eating disorder research. Method A systematic literature search was …

Introduction Meta-analytical evidence confirms a range of interventions, including
mindfulness, physical activity and sleep hygiene, can reduce psychological distress in …

This practical high-level guidebook offers an in-depth understanding of the newly emerging
clinical trial designs in adaptive trial designs and master protocols. Both concise and …

Adaptive designs are a class of methods for improving efficiency and patient benefit of
clinical trials. Although their use has increased in recent years, research suggests they are …

Background Adaptive clinical trials are growing in popularity as they are more flexible,
efficient and ethical than traditional fixed designs. However, notwithstanding their increased …

Background The expected value of sample information (EVSI) measures the expected
benefits that could be obtained by collecting additional data. Estimating EVSI using the …

We propose a short-cut heuristic approach to rapidly estimate value of information (VOI)
using information commonly reported in a research funding application to make a case for …

Objective There is uncertainty around whether, and under what circumstances, there is
value in embedding economic considerations into multi-arm, multi-stage (MAMS), adaptive …

Objectives Value-based trials aim to maximize the expected net benefit by balancing
technology adoption decisions and clinical trial costs. Adaptive trials offer additional …