Quantitative imaging of Gd nanoparticles in mice using benchtop cone-beam X-ray fluorescence computed tomography system

S Zhang, L Li, J Chen, Z Chen, W Zhang… - International journal of …, 2019 - mdpi.com
Nanoparticles (NPs) are currently under intensive research for their application in tumor
diagnosis and therapy. X-ray fluorescence computed tomography (XFCT) is considered a …

A high-sensitivity benchtop X-ray fluorescence emission tomography (XFET) system with a full-ring of X-ray imaging-spectrometers and a compound-eye collimation …

S Mandot, EM Zannoni, L Cai, X Nie… - IEEE transactions on …, 2024 - ieeexplore.ieee.org
The advent of metal-based drugs and metal nanoparticles as therapeutic agents in anti-
tumor treatment has motivated the advancement of X-ray fluorescence computed …

Full-field in vivo imaging of nanoparticles using benchtop cone-beam XFCT system with pixelated photon counting detector

L Li, S Zhang, W Zhang, H Lu - Physics in Medicine & Biology, 2023 - iopscience.iop.org
Objective. X-ray fluorescence computed tomography (XFCT) is a promising noninvasive
technique for in vivo imaging of high-Z elements (eg gadolinium (Gd) or gold (Au)). In this …

Full-field fan-beam x-ray fluorescence computed tomography with a conventional x-ray tube and photon-counting detectors for fast nanoparticle bioimaging

L Li, S Zhang, R Li, Z Chen - Optical Engineering, 2017 - spiedigitallibrary.org
X-ray fluorescence computed tomography (XFCT) was performed on a high-intensity
synchrotron radiation source or a pencil beam with a long exposure time due to the low …

Sheet beam x‐ray fluorescence computed tomography (XFCT) imaging of gold nanoparticles

CAS Dunning, M Bazalova‐Carter - Medical physics, 2018 - Wiley Online Library
Purpose X‐ray fluorescence computed tomography (XFCT) experiments have typically used
pencil beams for data acquisition, which yielded good quality images of gold nanoparticles …

A benchtop cone‐beam x‐ray fluorescence computed tomography (XFCT) system with a high‐power x‐ray source and transmission CT imaging capability

N Manohar, FJ Reynoso, SH Cho - Medical physics, 2018 - Wiley Online Library
Purpose This report describes upgrades and performance characterization of an
experimental benchtop cone‐beam x‐ray fluorescence computed tomography (XFCT) …

Pinhole X-ray fluorescence imaging of gadolinium and gold nanoparticles using polychromatic X-rays: a Monte Carlo study

S Jung, W Sung, SJ Ye - International Journal of Nanomedicine, 2017 - Taylor & Francis
This work aims to develop a Monte Carlo (MC) model for pinhole K-shell X-ray fluorescence
(XRF) imaging of metal nanoparticles using polychromatic X-rays. The MC model consisted …

Compton background elimination for in vivo x-ray fluorescence imaging of gold nanoparticles using convolutional neural network

S Jung, J Lee, H Cho, T Kim… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
This article reports the first application of a convolutional neural network (CNN) to in vivo X-
ray fluorescence (XRF) images of gold nanoparticles (GNPs) obtained by a benchtop X-ray …

Effect of detector placement on joint estimation in X-ray fluorescence emission tomography

H DeBrosse, LJ Meng… - IEEE transactions on …, 2023 - ieeexplore.ieee.org
Imaging the spatial distribution of low concentrations of metal is a growing problem of
interest with applications in medical and material sciences. X-ray fluorescence emission …

Joint estimation of metal density and attenuation maps with pencil beam XFET

H DeBrosse, T Chandler, LJ Meng… - IEEE transactions on …, 2022 - ieeexplore.ieee.org
X-ray fluorescence emission tomography (XFET) is an emerging imaging modality that
images the spatial distribution of metal without requiring biochemical modification or …