Quantification of liver fat content with CT and MRI: state of the art

J Starekova, D Hernando, PJ Pickhardt, SB Reeder - Radiology, 2021 - pubs.rsna.org
Hepatic steatosis is defined as pathologically elevated liver fat content and has many
underlying causes. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic …

Metabolic implications of pancreatic fat accumulation

R Wagner, SS Eckstein, H Yamazaki, F Gerst… - Nature Reviews …, 2022 - nature.com
Fat accumulation outside subcutaneous adipose tissue often has unfavourable effects on
systemic metabolism. In addition to non-alcoholic fatty liver disease, which has received …

[PDF][PDF] Noninvasive, quantitative assessment of liver fat by MRI‐PDFF as an endpoint in NASH trials

C Caussy, SB Reeder, CB Sirlin, R Loomba - Hepatology, 2018 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver
disease worldwide, and the progressive form of this condition, nonalcoholic steatohepatitis …

Head-to-head comparison between MEFIB, MAST, and FAST for detecting stage 2 fibrosis or higher among patients with NAFLD

BK Kim, N Tamaki, K Imajo, M Yoneda, N Sutter… - Journal of …, 2022 - Elsevier
Background & Aims Patients with non-alcoholic fatty liver disease (NAFLD) and significant
fibrosis (fibrosis stage≥ 2) are candidates for pharmacological trials. The aim of this study …

Quantitative MRI and spectroscopy of bone marrow

DC Karampinos, S Ruschke… - Journal of Magnetic …, 2018 - Wiley Online Library
Bone marrow is one of the largest organs in the human body, enclosing adipocytes,
hematopoietic stem cells, which are responsible for blood cell production, and mesenchymal …

Quantitative magnetic resonance imaging phantoms: a review and the need for a system phantom

KE Keenan, M Ainslie, AJ Barker… - Magnetic resonance …, 2018 - Wiley Online Library
The MRI community is using quantitative map** techniques to complement qualitative
imaging. For quantitative imaging to reach its full potential, it is necessary to analyze …

Osteoporosis and bone marrow adipose tissue

KM Beekman, G Duque, A Corsi, M Tencerova… - Current osteoporosis …, 2023 - Springer
Abstract Purpose of Review This review focuses on the recent findings regarding bone
marrow adipose tissue (BMAT) concerning bone health. We summarize the variations in …

Recommendations towards standards for quantitative MRI (qMRI) and outstanding needs

KE Keenan, JR Biller, JG Delfino… - Journal of magnetic …, 2019 - pmc.ncbi.nlm.nih.gov
BACKGROUND In light of the many positive contributions qualitative MRI already makes,
existing workflows and decades of experience with image interpretation, a legitimate first …

Quantification of liver fat content with unenhanced MDCT: phantom and clinical correlation with MRI proton density fat fraction

PJ Pickhardt, PM Graffy, SB Reeder… - American Journal of …, 2018 - ajronline.org
OBJECTIVE. The purpose of this study was to evaluate the relation between unenhanced
CT liver attenuation values and MRI-derived proton density fat fraction (PDFF) for estimation …

Fat fraction map** using magnetic resonance imaging: insight into pathophysiology

TJP Bray, MD Chouhan, S Punwani… - The British journal of …, 2017 - academic.oup.com
Adipose cells have traditionally been viewed as a simple, passive energy storage depot for
triglycerides. However, in recent years it has become clear that adipose cells are highly …