[HTML][HTML] An overview of coumarin as a versatile and readily accessible scaffold with broad-ranging biological activities

F Annunziata, C Pinna, S Dallavalle… - International Journal of …, 2020 - mdpi.com
Privileged structures have been widely used as an effective template for the research and
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …

Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review

C Zhao, KP Rakesh, L Ravidar, WY Fang… - European journal of …, 2019 - Elsevier
Sulfur (S VI) based moieties, especially, the sulfonyl or sulfonamide based analogues have
showed a variety of pharmacological properties, and its derivatives propose a high degree …

Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review

WY Fang, L Ravindar, KP Rakesh… - European Journal of …, 2019 - Elsevier
At present more than 250 FDA approved chlorine containing drugs were available in the
market and many pharmaceutically important drug candidates in pre-clinical trials. Thus, it is …

Therapeutic potential of coumarins as antiviral agents

MZ Hassan, H Osman, MA Ali, MJ Ahsan - European journal of medicinal …, 2016 - Elsevier
Coumarins have received a considerable attention in the last three decades as a lead
structures for the discovery of orally bioavailable non-peptidic antiviral agents. A lot of …

Sars-cov-2 host entry and replication inhibitors from Indian ginseng: an in-silico approach

RV Chikhale, SS Gurav, RB Patil, SK Sinha… - Journal of …, 2021 - Taylor & Francis
COVID-19 has ravaged the world and is the greatest of pandemics in modern human history,
in the absence of treatment or vaccine, the mortality and morbidity rates are very high. The …

Broad-spectrum antiviral properties of andrographolide

S Gupta, KP Mishra, L Ganju - Archives of virology, 2017 - Springer
Andrographolide, a diterpenoid, is known for its anti-inflammatory effects. It can be isolated
from various plants of the genus Andrographis, commonly known as 'creat'. This purified …

Antiviral and immunomodulation effects of Artemisia

SG Kshirsagar, RV Rao - Medicina, 2021 - mdpi.com
Background and Objectives: Artemisia is one of the most widely distributed genera of the
family Astraceae with more than 500 diverse species growing mainly in the temperate zones …

Evaluation of anti-dengue activity of Carica papaya aqueous leaf extract and its role in platelet augmentation

N Sharma, KP Mishra, S Chanda, V Bhardwaj… - Archives of …, 2019 - Springer
Dengue disease is characterized by a marked decrease in platelet count, which is life
threatening. In the present study, we investigated the antiviral activity of an aqueous extract …

Emerging paradigms of viral diseases and paramount role of natural resources as antiviral agents

RS Jansi, A Khusro, P Agastian, A Alfarhan… - Science of the Total …, 2021 - Elsevier
In the current scenario, the increasing prevalence of diverse microbial infections as well as
emergence and re-emergence of viral epidemics with high morbidity and mortality rates are …

COVID-19 and therapeutic drugs repurposing in hand: the need for collaborative efforts

Z Khan, Y Karataş, AF Ceylan, H Rahman - Le Pharmacien Hospitalier et …, 2021 - Elsevier
The novel pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible to cause coronavirus disease-2019 (COVID-19). It is a global pandemic disease …