Engineering macrophages for cancer immunotherapy and drug delivery

Y **a, L Rao, H Yao, Z Wang, P Ning… - Advanced …, 2020 - Wiley Online Library
Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …

Stealth nanoparticles in oncology: Facing the PEG dilemma

S Zalba, TLM Ten Hagen, C Burgui… - Journal of Controlled …, 2022 - Elsevier
Nanoparticles (Nps) have revolutionized the landscape of many treatments, by modifying not
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …

Infection microenvironment-related antibacterial nanotherapeutic strategies

Z Wang, X Liu, Y Duan, Y Huang - Biomaterials, 2022 - Elsevier
The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

Cell membrane coating nanotechnology

RH Fang, AV Kroll, W Gao, L Zhang - Advanced materials, 2018 - Wiley Online Library
Nanoparticle‐based therapeutic, prevention, and detection modalities have the potential to
greatly impact how diseases are diagnosed and managed in the clinic. With the wide range …

Platelet membrane‐camouflaged magnetic nanoparticles for ferroptosis‐enhanced cancer immunotherapy

Q Jiang, K Wang, X Zhang, B Ouyang, H Liu, Z Pang… - Small, 2020 - Wiley Online Library
Although cancer immunotherapy has emerged as a tremendously promising cancer therapy
method, it remains effective only for several cancers. Photoimmunotherapy (eg …

Macrophage cell membrane‐cloaked nanoplatforms for biomedical applications

J Lopes, D Lopes, M Pereira‐Silva, D Peixoto… - Small …, 2022 - Wiley Online Library
Biomimetic approaches utilize natural cell membrane‐derived nanovesicles to camouflage
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …

Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics

X Li, Y Gao, H Li, JP Majoral, X Shi, A Pich - Progress in Materials Science, 2023 - Elsevier
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

Stealth coating of nanoparticles in drug-delivery systems

SY Fam, CF Chee, CY Yong, KL Ho… - Nanomaterials, 2020 - mdpi.com
Nanoparticles (NPs) have emerged as a powerful drug-delivery tool for cancer therapies to
enhance the specificity of drug actions, while reducing the systemic side effects …

[HTML][HTML] Recent advances in long-acting drug delivery systems for anticancer drug

C Pacheco, A Baiao, T Ding, W Cui… - Advanced Drug Delivery …, 2023 - Elsevier
The use of systemic anticancer chemotherapy is intrinsically limited by its toxicity. Whether
dealing with small molecules or biopharmaceuticals, after systemic administration, small …

[HTML][HTML] Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application

Q **a, Y Zhang, Z Li, X Hou, N Feng - Acta Pharmaceutica Sinica B, 2019 - Elsevier
Erythrocytes (red blood cells, RBCs) are the most abundant circulating cells in the blood and
have been widely used in drug delivery systems (DDS) because of their features of …