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How the epigenome integrates information and reshapes the synapse
In the past few decades, the field of neuroepigenetics has investigated how the brain
encodes information to form long-lasting memories that lead to stable changes in behaviour …
encodes information to form long-lasting memories that lead to stable changes in behaviour …
Getting neural circuits into shape with semaphorins
RJ Pasterkamp - Nature Reviews Neuroscience, 2012 - nature.com
Semaphorins are key players in the control of neural circuit development. Recent studies
have uncovered several exciting and novel aspects of neuronal semaphorin signalling in …
have uncovered several exciting and novel aspects of neuronal semaphorin signalling in …
MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation
CJ Li, P Cheng, MK Liang, YS Chen, Q Lu… - The Journal of clinical …, 2015 - jci.org
Bone marrow mesenchymal stem cells (BMSCs) exhibit an age-dependent reduction in
osteogenesis that is accompanied by an increased propensity toward adipocyte …
osteogenesis that is accompanied by an increased propensity toward adipocyte …
APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p
K Wang, CY Liu, LY Zhou, JX Wang, M Wang… - Nature …, 2015 - nature.com
The abnormal autophagy is associated with a variety of cardiovascular diseases. Long
noncoding RNAs (lncRNAs) are emerging as new factors in gene regulation, but how …
noncoding RNAs (lncRNAs) are emerging as new factors in gene regulation, but how …
[HTML][HTML] MicroRNAs shape the neuronal landscape
E McNeill, D Van Vactor - Neuron, 2012 - cell.com
The nervous system equips us with capability to adapt to many conditions and
circumstances. We rely on an armamentarium of intricately formed neural circuits for many of …
circumstances. We rely on an armamentarium of intricately formed neural circuits for many of …
Semaphorin signalling during development
BC Jongbloets, RJ Pasterkamp - Development, 2014 - journals.biologists.com
Semaphorins are secreted and membrane-associated proteins that regulate many different
developmental processes, including neural circuit assembly, bone formation and …
developmental processes, including neural circuit assembly, bone formation and …
miRNAs in synapse development and synaptic plasticity
Z Hu, Z Li - Current opinion in neurobiology, 2017 - Elsevier
Highlights•miRNAs and RISC are located near synapses.•miRNAs regulate local protein
synthesis in dendrites and axons.•miRNAs play important roles in synapse development and …
synthesis in dendrites and axons.•miRNAs play important roles in synapse development and …
MicroRNA-188-5p suppresses tumor cell proliferation and metastasis by directly targeting FGF5 in hepatocellular carcinoma
F Fang, R Chang, L Yu, X Lei, S **ao, H Yang… - Journal of …, 2015 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) is one of the most common
malignancies worldwide. However, the detailed molecular mechanisms underlying HCC …
malignancies worldwide. However, the detailed molecular mechanisms underlying HCC …
Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review
MJ Millan - Progress in neurobiology, 2017 - Elsevier
The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …
MicroRNAs and synapse turnover in Alzheimer's disease
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder characterized by the
accumulation of amyloid-beta plaques and neurofibrillary tangles in the brain, leading to …
accumulation of amyloid-beta plaques and neurofibrillary tangles in the brain, leading to …