Current status of the diagnosis of early-stage pancreatic ductal adenocarcinoma

K Nakaoka, E Ohno, N Kawabe, T Kuzuya, K Funasaka… - Diagnostics, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) can be treated with surgery, chemotherapy, and
radiotherapy. Despite medical progress in each field in recent years, it is still insufficient for …

Exploring the clinical utility of pancreatic cancer circulating tumor cells

D Yeo, A Bastian, H Strauss, P Saxena… - International Journal of …, 2022 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is the most frequent pancreatic cancer type,
characterized by a dismal prognosis due to late diagnosis, frequent metastases, and limited …

Liquid biopsy in pancreatic cancer: are we ready to apply it in the clinical practice?

V Heredia-Soto, N Rodríguez-Salas, J Feliu - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the tumors with the
highest mortality, for which survival has hardly changed in the last 40 years. This high …

Adherence to NCCN genetic testing guidelines in pancreatic cancer and impact on treatment

F Crowley, S Gandhi, M Rudshteyn, M Sehmbhi… - The …, 2023 - academic.oup.com
Abstract Introduction National Comprehensive Cancer Network (NCCN) 2019 Guidelines
recommend universal germline (GL) testing for patients (pts) with pancreatic cancer (PC) …

The emerging role of circulating tumor DNA in non-colorectal gastrointestinal cancers

MS Lee, AO Kaseb, S Pant - Clinical Cancer Research, 2023 - aacrjournals.org
Assays to detect circulating tumor DNA (ctDNA) have multiple clinically important
applications in management of multiple types of gastrointestinal cancers. Different …

Neoadjuvant chemotherapy or upfront surgery in localized pancreatic cancer: a contemporary analysis

PLS Uson Junior, L Carvalho, MLC Fernandes… - Scientific Reports, 2022 - nature.com
Neoadjuvant chemotherapy is considered a new treatment option for potentially resectable
pancreatic cancer. However, data are not well established on overall survival and delaying …

[HTML][HTML] Circulating tumor DNA-based genomic profiling assays in adult solid tumors for precision oncology: recent advancements and future challenges

HT Chan, YM Chin, SK Low - Cancers, 2022 - mdpi.com
Simple Summary The use of liquid biopsy for tumor genomic profiling to identify genomic
biomarkers for targeted therapies has revolutionized the clinical practice in oncology …

Current applications of liquid biopsy in gastrointestinal cancer disease—from early cancer detection to individualized cancer treatment

P David, A Mittelstädt, D Kouhestani, A Anthuber… - Cancers, 2023 - mdpi.com
Simple Summary Gastrointestinal (GI) cancers are a common cancer, affecting both men
and women, normally diagnosed through tissue biopsies in combination with imaging …

Deconstructing pancreatic cancer using next generation-omic technologies–from discovery to knowledge-guided platforms for better patient management

D Schreyer, JP Neoptolemos, ST Barry… - Frontiers in Cell and …, 2022 - frontiersin.org
Comprehensive molecular landsca** studies reveal a potentially brighter future for
pancreatic ductal adenocarcinoma (PDAC) patients. Blood-borne biomarkers obtained from …

[HTML][HTML] Prognostic role of cell-free DNA biomarkers in pancreatic adenocarcinoma: A systematic review and meta–analysis

S Bunduc, N Gede, S Váncsa, V Lillik, S Kiss… - Critical Reviews in …, 2022 - Elsevier
This systematic review and meta-analysis evaluated the prognostic role of cell-free DNA
(cfDNA) in pancreatic ductal adenocarcinoma (PDAC). Eligible studies reported differences …