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Advances in CRISPR therapeutics
The clustered regularly interspaced short palindromic repeats (CRISPR) renaissance was
catalysed by the discovery that RNA-guided prokaryotic CRISPR-associated (Cas) proteins …
catalysed by the discovery that RNA-guided prokaryotic CRISPR-associated (Cas) proteins …
CRISPR technologies and the search for the PAM-free nuclease
D Collias, CL Beisel - Nature communications, 2021 - nature.com
The ever-expanding set of CRISPR technologies and their programmable RNA-guided
nucleases exhibit remarkable flexibility in DNA targeting. However, this flexibility comes with …
nucleases exhibit remarkable flexibility in DNA targeting. However, this flexibility comes with …
Plant breeding advancements with “CRISPR-Cas” genome editing technologies will assist future food security
M Ahmad - Frontiers in plant science, 2023 - frontiersin.org
Genome editing techniques are being used to modify plant breeding, which might increase
food production sustainably by 2050. A product made feasible by genome editing is …
food production sustainably by 2050. A product made feasible by genome editing is …
Engineered probiotics
J Ma, Y Lyu, X Liu, X Jia, F Cui, X Wu, S Deng… - Microbial cell …, 2022 - Springer
Engineered probiotics are a kind of new microorganisms produced by modifying original
probiotics through gene editing. With the continuous development of tools and technology …
probiotics through gene editing. With the continuous development of tools and technology …
Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9
Thermostable clustered regularly interspaced short palindromic repeats (CRISPR) and
CRISPR-associated (Cas9) enzymes could improve genome-editing efficiency and delivery …
CRISPR-associated (Cas9) enzymes could improve genome-editing efficiency and delivery …
Sensitive and portable signal readout strategies boost point-of-care CRISPR/Cas12a biosensors
T Li, N Cheng - ACS sensors, 2023 - ACS Publications
Point-of-care (POC) detection is getting more and more attention in many fields due to its
accuracy and on-site test property. The CRISPR/Cas12a system is endowed with excellent …
accuracy and on-site test property. The CRISPR/Cas12a system is endowed with excellent …
A review on advanced CRISPR-based genome-editing tools: base editing and prime editing
A Saber Sichani, M Ranjbar, M Baneshi… - Molecular …, 2023 - Springer
In the field of medicine, it is axiomatic that the need of a precise gene-editing tool is critical to
employ therapeutic approaches toward pathogenic mutations, occurring in human genome …
employ therapeutic approaches toward pathogenic mutations, occurring in human genome …
Nucleic acid-assisted CRISPR-Cas systems for advanced biosensing and bioimaging
Nucleic acid molecules possess many superior properties, including high designability and
structural predictability, making them attractive biosensing and bioimaging tools. The …
structural predictability, making them attractive biosensing and bioimaging tools. The …
Genome editing and beyond: what does it mean for the future of plant breeding?
Main conclusion Genome editing offers revolutionized solutions for plant breeding to sustain
food production to feed the world by 2050. Therefore, genome-edited products are …
food production to feed the world by 2050. Therefore, genome-edited products are …
CRISPR/Cas9 in lepidopteran insects: Progress, application and prospects
Clustered regularly spaced short palindrome repeats (CRISPR) structure family forms the
acquired immune system in bacteria and archaea. Recent advances in CRISPR/Cas …
acquired immune system in bacteria and archaea. Recent advances in CRISPR/Cas …