Adoptive transfer of chimeric antigen receptor (CAR) T lymphocytes is a powerful technology
that has revolutionized the way we conceive immunotherapy. The impressive clinical results …

Next-generation sequencing (NGS) technologies using DNA, RNA, or methylation
sequencing have impacted enormously on the life sciences. NGS is the choice for large …

A complete telomere-to-telomere (T2T) finished genome has been the long pursuit of
genomic research. Through generating deep coverage ultralong Oxford Nanopore …

Cereal grasses of the Triticeae tribe have been the major food source in temperate regions
since the dawn of agriculture. Their large genomes are characterized by a high content of …

Long terminal repeat retrotransposons (LTR-RTs) are prevalent in plant genomes. The
identification of LTR-RTs is critical for achieving high-quality gene annotation. Based on the …

One-step and two-step pathways are proposed to synthesize cytokinin in plants. The one-
step pathway is mediated by LONELY GUY (LOG) proteins. However, the enzyme for the two …

The genus Oryza is a model system for the study of molecular evolution over time scales
ranging from a few thousand to 15 million years. Using 13 reference genomes spanning the …

We report an improved draft nucleotide sequence of the 2.3-gigabase genome of maize, an
important crop plant and model for biological research. Over 32,000 genes were predicted …

Transposable elements (TEs) are the key players in generating genomic novelty by a
combination of the chromosome rearrangements they cause and the genes that come under …

2012 still-prevalent view that every bit of an organism's DNA has a specific function crafted
by selection. Thus, both papers promoted Dawkins' concept of “selfish DNA”—the notion that …