The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

ROS and RNS signalling: adaptive redox switches through oxidative/nitrosative protein modifications

NT Moldogazieva, IM Mokhosoev… - Free radical …, 2018 - Taylor & Francis
Over the last decade, a dual character of cell response to oxidative stress, eustress versus
distress, has become increasingly recognized. A growing body of evidence indicates that …

Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery

CE Paulsen, KS Carroll - Chemical reviews, 2013 - ACS Publications
Reactive oxygen, nitrogen, and sulfur species, referred to as ROS, RNS, and RSS,
respectively, are produced during normal cell function and in response to various stimuli. An …

Protein S-nitrosylation: determinants of specificity and enzymatic regulation of S-nitrosothiol-based signaling

CT Stomberski, DT Hess, JS Stamler - Antioxidants & redox …, 2019 - liebertpub.com
Significance: Protein S-nitrosylation, the oxidative modification of cysteine by nitric oxide
(NO) to form protein S-nitrosothiols (SNOs), mediates redox-based signaling that conveys, in …

[HTML][HTML] S-nitrosylation: an emerging paradigm of redox signaling

V Fernando, X Zheng, Y Walia, V Sharma, J Letson… - Antioxidants, 2019 - mdpi.com
Nitric oxide (NO) is a highly reactive molecule, generated through metabolism of L-arginine
by NO synthase (NOS). Abnormal NO levels in mammalian cells are associated with multiple …

Nitric oxide function in plant biology: a redox cue in deconvolution

M Yu, L Lamattina, SH Spoel, GJ Loake - New phytologist, 2014 - Wiley Online Library
Nitric oxide (NO), a gaseous, redox‐active small molecule, is gradually becoming
established as a central regulator of growth, development, immunity and environmental …

Chemical methods for map** cysteine oxidation

LJ Alcock, MV Perkins, JM Chalker - Chemical Society Reviews, 2018 - pubs.rsc.org
Cysteine residues in proteins are subject to diverse redox chemistry. Oxidation of cysteine to
S-nitrosocysteine, cysteine sulfenic and sulfinic acids, disulfides and persulfides are a few …

pLogo: a probabilistic approach to visualizing sequence motifs

JP O'shea, MF Chou, SA Quader, JK Ryan… - Nature …, 2013 - nature.com
Methods for visualizing protein or nucleic acid motifs have traditionally relied upon residue
frequencies to graphically scale character heights. We describe the pLogo, a motif …

[HTML][HTML] The role of nitric oxide in brain disorders: Autism spectrum disorder and other psychiatric, neurological, and neurodegenerative disorders

MK Tripathi, M Kartawy, H Amal - Redox Biology, 2020 - Elsevier
Nitric oxide (NO) is a multifunctional signalling molecule and a neurotransmitter that plays
an important role in physiological and pathophysiological processes. In physiological …

S-nitrosoglutathione

KA Broniowska, AR Diers, N Hogg - Biochimica et Biophysica Acta (BBA) …, 2013 - Elsevier
BACKGROUND: S-Nitrosoglutathione (GSNO) is the S-nitrosated derivative of glutathione
and is thought to be a critical mediator of the down stream signaling effects of nitric oxide …