25th anniversary article: supramolecular materials for regenerative medicine

J Boekhoven, SI Stupp - Advanced materials, 2014 - Wiley Online Library
In supramolecular materials, molecular building blocks are designed to interact with one
another via non‐covalent interactions in order to create function. This offers the opportunity …

Elastin-based materials: promising candidates for cardiac tissue regeneration

I Gonzalez de Torre, M Alonso… - … in bioengineering and …, 2020 - frontiersin.org
Stroke and cardiovascular episodes are still some of the most common diseases worldwide,
causing millions of deaths and costing billions of Euros to healthcare systems. The use of …

Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair

MJ Webber, J Tongers, CJ Newcomb… - Proceedings of the …, 2011 - pnas.org
There is great demand for the development of novel therapies for ischemic cardiovascular
disease, a leading cause of morbidity and mortality worldwide. We report here on the …

In vivo studies on angiogenic activity of two designer self-assembling peptide scaffold hydrogels in the chicken embryo chorioallantoic membrane

X Liu, X Wang, A Horii, X Wang, L Qiao, S Zhang… - Nanoscale, 2012 - pubs.rsc.org
The rapid promotion of angiogenesis is critical for tissue engineering and regenerative
medicine. The angiogenic activity of tissue-engineered scaffolds has already been the major …

Designed multifunctional spider silk enabled by genetically encoded click chemistry

B Jiang, SY Tan, S Fang, X Feng… - Advanced Functional …, 2023 - Wiley Online Library
Spider silk is recognized for its exceptional mechanical properties and biocompatibility,
making it a versatile platform for develo** functional materials. In this study, a modular …

In vivo properties of the proangiogenic peptide QK

G Santulli, M Ciccarelli, G Palumbo… - Journal of translational …, 2009 - Springer
The main regulator of neovascularization is Vascular Endothelial Growth Factor (VEGF). We
recently demonstrated that QK, a de novo engineered VEGF mimicking peptide, shares in …

Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis

F Finetti, A Basile, D Capasso, S Di Gaetano… - Biochemical …, 2012 - Elsevier
Vascular endothelial growth factor (VEGF) is the main regulator of physiological and
pathological angiogenesis. Low molecular weight molecules able to stimulate angiogenesis …

Tethering QK peptide to enhance angiogenesis in elastin-like recombinamer (ELR) hydrogels

T Flora, IG de Torre, M Alonso… - Journal of Materials …, 2019 - Springer
The development of new capillary networks in engineered constructs is essential for their
survival and their integration with the host tissue. It has recently been demonstrated that ELR …

Biodegradable mesoporous silica nanocarrier bearing angiogenic QK peptide and dexamethasone for accelerating angiogenesis in bone regeneration

P Sun, Q Zhang, W Nie, X Zhou, L Chen… - ACS Biomaterials …, 2019 - ACS Publications
In the repair of large segmental bone defects, bone tissue is often unable to heal due to the
destruction of the vascular network near the wound site. An ideal bone repair material …

Depot-based delivery systems for pro-angiogenic peptides: a review

AH Van Hove, DSW Benoit - Frontiers in bioengineering and …, 2015 - frontiersin.org
Insufficient vascularization currently limits the size and complexity for all tissue engineering
approaches. Additionally, increasing or re-initiating blood flow is the first step toward …