Originally identified in studies of cellular resistance to viral infection, interferon (IFN)-γ is now
known to represent a distinct member of the IFN family and plays critical roles not only in …

Interferon gamma has long been studied as a critical mediator of tumor immunity. In recent
years, the complexity of cellular interactions that take place in the tumor microenvironment …

Cervical cancer is responsible for 10–15% of cancer-related deaths in women worldwide,.
The aetiological role of infection with high-risk human papilloma viruses (HPVs) in cervical …

Throughout the body, T cells monitor MHC-bound ligands expressed on the surface of
essentially all cell types. MHC ligands that trigger a T cell immune response are referred to …

Abstract Angiotensin-converting enzyme (ACE)—a zinc-dependent dicarboxypeptidase with
two catalytic domains—plays a major part in blood pressure regulation by converting …

Systemic lupus erythematosus (SLE) is a typical autoimmune disease with a complex
pathogenesis and genetic predisposition. With continued understanding of this disease, it …

Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary
immune responses. DCs capture and transfer information from the outside world to the cells …

Stem cells are critical for the maintenance of many tissues, but whether their integrity is
maintained in the face of immunity is unclear. Here we found that cycling epithelial stem …

-Cubre la epidemiología, la etiología, la patología, la microbiología, la inmunología y el
tratamiento de los agentes infecciosos en mayor profundidad que ninguna otra obra de la …

It is well known that many tumours are potentially immunogenic, as corroborated by the
presence of tumour-specific immune responses in vivo. Nonetheless, spontaneous …