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Neural tube closure: cellular, molecular and biomechanical mechanisms
Neural tube closure has been studied for many decades, across a range of vertebrates, as a
paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the …
paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the …
Tissue stiffness dictates development, homeostasis, and disease progression
AM Handorf, Y Zhou, MA Halanski, WJ Li - Organogenesis, 2015 - Taylor & Francis
Tissue development is orchestrated by the coordinated activities of both chemical and
physical regulators. While much attention has been given to the role that chemical regulators …
physical regulators. While much attention has been given to the role that chemical regulators …
Organization and execution of the epithelial polarity programme
E Rodriguez-Boulan, IG Macara - Nature reviews Molecular cell biology, 2014 - nature.com
Epithelial cells require apical–basal plasma membrane polarity to carry out crucial vectorial
transport functions and cytoplasmic polarity to generate different cell progenies for tissue …
transport functions and cytoplasmic polarity to generate different cell progenies for tissue …
Self-organizing optic-cup morphogenesis in three-dimensional culture
Balanced organogenesis requires the orchestration of multiple cellular interactions to create
the collective cell behaviours that progressively shape develo** tissues. It is currently …
the collective cell behaviours that progressively shape develo** tissues. It is currently …
Apical constriction: themes and variations on a cellular mechanism driving morphogenesis
AC Martin, B Goldstein - Development, 2014 - journals.biologists.com
Apical constriction is a cell shape change that promotes tissue remodeling in a variety of
homeostatic and developmental contexts, including gastrulation in many organisms and …
homeostatic and developmental contexts, including gastrulation in many organisms and …
Integer topological defects organize stresses driving tissue morphogenesis
P Guillamat, C Blanch-Mercader, G Pernollet… - Nature materials, 2022 - nature.com
Tissues acquire function and shape via differentiation and morphogenesis. Both processes
are driven by coordinating cellular forces and shapes at the tissue scale, but general …
are driven by coordinating cellular forces and shapes at the tissue scale, but general …
Cadherin adhesion and mechanotransduction
DE Leckband, J de Rooij - Annual review of cell and …, 2014 - annualreviews.org
Cadherins are the principal adhesion proteins at intercellular junctions and function as the
biochemical Velcro that binds cells together. Besides this mechanical function, cadherin …
biochemical Velcro that binds cells together. Besides this mechanical function, cadherin …
Mechanical control of tissue and organ development
Many genes and molecules that drive tissue patterning during organogenesis and tissue
regeneration have been discovered. Yet, we still lack a full understanding of how these …
regeneration have been discovered. Yet, we still lack a full understanding of how these …
Mechanobiology and developmental control
T Mammoto, A Mammoto… - Annual review of cell and …, 2013 - annualreviews.org
Morphogenesis is the remarkable process by which cells self-assemble into complex tissues
and organs that exhibit specialized form and function during embryological development …
and organs that exhibit specialized form and function during embryological development …
Light-regulated collective contractility in a multicellular choanoflagellate
T Brunet, BT Larson, TA Linden, MJA Vermeij… - Science, 2019 - science.org
Collective cell contractions that generate global tissue deformations are a signature feature
of animal movement and morphogenesis. However, the origin of collective contractility in …
of animal movement and morphogenesis. However, the origin of collective contractility in …