Obesity is a disorder with an increasing prevalence, which impairs the life quality of patients
and intensifies societal health care costs. The development of safe and innovative …

Ethnopharmacological relevance Mulberry leaves have been used as traditional
hypoglycemic medicine-food plant for thousand years in China. According to traditional …

In the last decade, the incidence of obesity has increased dramatically worldwide, reaching
a dangerous pandemic spread. This condition has serious public health implications as it …

Diabetic nephropathy (DN) as a global health concern is closely related to inflammation and
oxidation. Isoliquiritigenin (ISL), a natural flavonoid compound, has been demonstrated to …

Elevated levels of reactive oxygen species (ROS) are a hallmark of obesity. Peroxiredoxin 5
(Prx5), which is a cysteine-dependent peroxidase enzyme, has an intensive ROS …

Isoliquiritigenin (ISL) is a flavonoid with a chalcone structure extracted from the natural herb
Glycyrrhiza glabra. Its anti-inflammatory, antibacterial, antioxidant, and anticancer activities …

Inhibition of adipocyte differentiation can be used as a strategy for preventing adipose tissue
expansion and, consequently, for obesity management. Since reactive oxygen species …

Isoliquiritigenin (ISL), a flavonoid derived from licorice root, has diverse biological and
pharmacological properties. This study aimed to investigate the hepatoprotective effects and …

Isoliquiritigenin (ILG) is a flavonoid constituent of Glycyrrhizae plants. The current study
investigated the effects of ILG on diet-induced obesity and metabolic diseases. C57BL/6J …

Nonalcoholic fatty liver disease (NAFLD), a metabolic disease, has received wide attention
worldwide. However, there is no approved effective drug for NAFLD treatment. In the study …