Machine learning for medical imaging: methodological failures and recommendations for the future

G Varoquaux, V Cheplygina - NPJ digital medicine, 2022 - nature.com
Research in computer analysis of medical images bears many promises to improve patients'
health. However, a number of systematic challenges are slowing down the progress of the …

Establishment of best practices for evidence for prediction: a review

RA Poldrack, G Huckins, G Varoquaux - JAMA psychiatry, 2020 - jamanetwork.com
Importance Great interest exists in identifying methods to predict neuropsychiatric disease
states and treatment outcomes from high-dimensional data, including neuroimaging and …

Reproducible brain-wide association studies require thousands of individuals

S Marek, B Tervo-Clemmens, FJ Calabro, DF Montez… - Nature, 2022 - nature.com
Magnetic resonance imaging (MRI) has transformed our understanding of the human brain
through well-replicated map** of abilities to specific structures (for example, lesion …

Brain–phenotype models fail for individuals who defy sample stereotypes

AS Greene, X Shen, S Noble, C Horien, CA Hahn… - Nature, 2022 - nature.com
Individual differences in brain functional organization track a range of traits, symptoms and
behaviours,,,,,,,,,,–. So far, work modelling linear brain–phenotype relationships has …

Machine learning algorithm validation with a limited sample size

A Vabalas, E Gowen, E Poliakoff, AJ Casson - PloS one, 2019 - journals.plos.org
Advances in neuroimaging, genomic, motion tracking, eye-tracking and many other
technology-based data collection methods have led to a torrent of high dimensional …

Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities

KD Davis, N Aghaeepour, AH Ahn, MS Angst… - Nature Reviews …, 2020 - nature.com
Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …

Big-data science in porous materials: materials genomics and machine learning

KM Jablonka, D Ongari, SM Moosavi, B Smit - Chemical reviews, 2020 - ACS Publications
By combining metal nodes with organic linkers we can potentially synthesize millions of
possible metal–organic frameworks (MOFs). The fact that we have so many materials opens …

Evaluating machine learning models and their diagnostic value

G Varoquaux, O Colliot - Machine learning for brain disorders, 2023 - Springer
This chapter describes model validation, a crucial part of machine learning whether it is to
select the best model or to assess performance of a given model. We start by detailing the …

Prediction: coveted, yet forsaken? Introducing a cross‐validated predictive ability test in partial least squares path modeling

BD Liengaard, PN Sharma, GTM Hult… - Decision …, 2021 - Wiley Online Library
Management researchers often develop theories and policies that are forward‐looking. The
prospective outlook of predictive modeling, where a model predicts unseen or new data, can …

Machine learning for precision psychiatry: opportunities and challenges

D Bzdok, A Meyer-Lindenberg - Biological Psychiatry: Cognitive …, 2018 - Elsevier
The nature of mental illness remains a conundrum. Traditional disease categories are
increasingly suspected to misrepresent the causes underlying mental disturbance. Yet …