Insights and opportunities for deep brain stimulation as a brain circuit intervention

WJ Neumann, A Horn, AA Kühn - Trends in Neurosciences, 2023 - cell.com
Deep brain stimulation (DBS) is an effective treatment and has provided unique insights into
the dynamic circuit architecture of brain disorders. This Review illustrates our current …

[HTML][HTML] Probing responses to deep brain stimulation with functional magnetic resonance imaging

A Loh, D Gwun, CT Chow, A Boutet, J Tasserie… - Brain stimulation, 2022 - Elsevier
Background Deep brain stimulation (DBS) is an established treatment for certain movement
disorders and has additionally shown promise for various psychiatric, cognitive, and seizure …

Proceedings of the ninth annual deep brain stimulation think tank: advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, pain …

JK Wong, G Deuschl, R Wolke, H Bergman… - Frontiers in Human …, 2022 - frontiersin.org
DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based
participants largely in person and overseas participants joining by video conferencing …

Deep brain stimulation of the central thalamus restores arousal and motivation in a zolpidem-responsive patient with akinetic mutism after severe brain injury

H Arnts, P Tewarie, W van Erp, R Schuurman… - Scientific reports, 2024 - nature.com
After severe brain injury, zolpidem is known to cause spectacular, often short-lived,
restorations of brain functions in a small subgroup of patients. Previously, we showed that …

Back to the technologies themselves: phenomenological turn within postphenomenology

D Mykhailov, N Liberati - Phenomenology and the Cognitive Sciences, 2023 - Springer
This paper revives phenomenological elements to have a better framework for addressing
the implications of technologies on society. For this reason, we introduce the motto “back to …

Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data

M Nazmuddin, IH Philippens, T van Laar - Scientific reports, 2021 - nature.com
Deep brain stimulation (DBS) of the nucleus basalis of Meynert (NBM) has been clinically
investigated in Alzheimer's disease (AD) and Lewy body dementia (LBD). However, the …

Electrophysiological approaches to informing therapeutic interventions with deep brain stimulation

A Asadi, AI Wiesman, C Wiest, S Baillet, H Tan… - npj Parkinson's …, 2025 - nature.com
Neuromodulation therapy comprises a range of non-destructive and adjustable methods for
modulating neural activity using electrical stimulations, chemical agents, or mechanical …

Applications of OPM-MEG for translational neuroscience: a perspective

M Brickwedde, P Anders, AA Kühn, R Lofredi… - Translational …, 2024 - nature.com
Magnetoencephalography (MEG) allows the non-invasive measurement of brain activity at
millisecond precision combined with localization of the underlying generators. So far, MEG …

Revealing connectivity patterns of deep brain stimulation efficacy in Parkinson's disease

E Výtvarová, M Lamoš, J Hlinka, S Goldemundová… - Scientific Reports, 2024 - nature.com
The aim of this work was to study the effect of deep brain stimulation of the subthalamic
nucleus (STN-DBS) on the subnetwork of subcortical and cortical motor regions and on the …

Translating pathological brain activity primers in Parkinson's disease research

D Mirzac, SL Kreis, HJ Luhmann… - Research, 2023 - spj.science.org
Translational experimental approaches that help us better trace Parkinson's disease (PD)
pathophysiological mechanisms leading to new therapeutic targets are urgently needed. In …