Candida albicans is the most common fungal pathogen of humans and has developed an
extensive repertoire of putative virulence mechanisms that allows successful colonization …

The cell wall is essential to nearly every aspect of the biology and pathogenicity of Candida
albicans. Although it was intially considered an almost inert cellular structure that protected …

Azole antifungal agents, and especially fluconazole, have been used widely to treat
oropharyngeal candidiasis in patients with AIDS. An increasing number of cases of clinical …

The construction of Candida albicans mutants by targeted gene disruption usually depends
on the use of nutritional markers for the selection of prototrophic transformants from …

Candida albicans is a facultative pathogenic micro‐organism that has developed several
virulence traits enabling invasion of host tissues and avoidance of host defence …

The Candida albicans cell wall maintains the structural integrity of the organism in addtion to
providing a physical contact interface with the environment. The major components of the …

The ALS gene family of Candida albicans encodes large cell-surface glycoproteins that are
implicated in the process of adhesion to host surfaces. ALS genes are also found in other …

Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Resistance to azole antifungal agents in Candida albicans can be mediated by multidrug
efflux transporters. In a previous study, we identified at least two such transporters, Cdr1p …

We have characterized CaNrg1 from Candida albicans, the major fungal pathogen in
humans. CaNrg1 contains a zinc finger domain that is conserved in transcriptional …