Micro-electrode-dot-array digital microfluidic biochips: Technology, design automation, and test techniques

Z Zhong, Z Li, K Chakrabarty, TY Ho… - IEEE Transactions on …, 2018 - ieeexplore.ieee.org
Digital microfluidic biochips (DMFBs) are being increasingly used for DNA sequencing, point-
of-care clinical diagnostics, and immunoassays. DMFBs based on a micro-electrode-dot …

Reliability issues in state-of-the-art microfluidic biochips: A survey

D Gountia - IETE Technical Review, 2023 - Taylor & Francis
Microfluidic biochips are a prominent class of lab-on-a-chip, ie LoC system, guided with
some activation sequences devised for a bioprotocol to manipulate fluids used in biomedical …

Introducing STRATOS: A cloud broker service

P Pawluk, B Simmons, M Smit, M Litoiu… - 2012 IEEE fifth …, 2012 - ieeexplore.ieee.org
This paper introduces a cloud broker service (STRATOS) which facilitates the deployment
and runtime management of cloud application topologies using cloud elements/services …

Reactant minimization during sample preparation on digital microfluidic biochips using skewed mixing trees

JD Huang, CH Liu, TW Chiang - Proceedings of the International …, 2012 - dl.acm.org
Sample preparation is an indispensable process to biochemical reactions. Original reactants
are usually diluted to the solutions with desirable concentrations. Since the reactants, like …

An open-source compiler and PCB synthesis tool for digital microfluidic biochips

D Grissom, C Curtis, S Windh, C Phung… - INTEGRATION, the VLSI …, 2015 - Elsevier
This paper describes a publicly available, open source software framework designed to
support research efforts on algorithms and control for digital microfluidic biochips (DMFBs) …

A reagent-saving mixing algorithm for preparing multiple-target biochemical samples using digital microfluidics

YL Hsieh, TY Ho, K Chakrabarty - IEEE Transactions on …, 2012 - ieeexplore.ieee.org
Recent advances in digital microfluidics have led to the promise of miniaturized laboratories,
with the associated advantages of high sensitivity and less human-induced errors. Front-end …

Reactant and waste minimization in multitarget sample preparation on digital microfluidic biochips

JD Huang, CH Liu, HS Lin - IEEE Transactions on Computer …, 2013 - ieeexplore.ieee.org
Sample preparation is one of essential processes in biochemical reactions. Raw reactants
are diluted in this process to achieve given target concentrations. A bioassay may require …

Error-correcting sample preparation with cyberphysical digital microfluidic lab-on-chip

S Poddar, S Ghoshal, K Chakrabarty… - ACM Transactions on …, 2016 - dl.acm.org
Digital (droplet-based) microfluidic technology offers an attractive platform for implementing
a wide variety of biochemical laboratory protocols, such as point-of-care diagnosis, DNA …

A network-flow-based optimal sample preparation algorithm for digital microfluidic biochips

TA Dinh, S Yamashita, TY Ho - 2014 19th Asia and South …, 2014 - ieeexplore.ieee.org
Sample preparation, which is a front-end process to produce droplets of the desired target
concentrations from input reagents, plays a pivotal role in every assay, laboratory, and …

Droplet size-aware and error-correcting sample preparation using micro-electrode-dot-array digital microfluidic biochips

Z Li, KYT Lai, K Chakrabarty, TY Ho… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
Sample preparation in digital microfluidics refers to the generation of droplets with target
concentrations for on-chip biochemical applications. In recent years, digital microfluidic …