Mass spectrometry-based detection and assignment of protein posttranslational modifications
Recent advances in mass spectrometry (MS)-based proteomics allow the identification and
quantitation of thousands of posttranslational modification (PTM) sites in a single …
quantitation of thousands of posttranslational modification (PTM) sites in a single …
The role of electron transfer dissociation in modern proteomics
(MS) and MS-driven proteomics have continued to develop as the premier tools for
characterizing proteome composition, structure, and function. 2 The new era of proteomics …
characterizing proteome composition, structure, and function. 2 The new era of proteomics …
Protein methylation in mitochondria
Many proteins are modified by posttranslational methylation, introduced by a number of
methyltransferases (MTases). Protein methylation plays important roles in modulating …
methyltransferases (MTases). Protein methylation plays important roles in modulating …
Protein arginine methylation: a prominent modification and its demethylation
Arginine methylation of histones is one mechanism of epigenetic regulation in eukaryotic
cells. Methylarginines can also be found in non-histone proteins involved in various different …
cells. Methylarginines can also be found in non-histone proteins involved in various different …
NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex I
Complex I (NADH ubiquinone oxidoreductase) in mammalian mitochondria is an L-shaped
assembly of 44 subunits. One arm is embedded in the inner membrane with the other …
assembly of 44 subunits. One arm is embedded in the inner membrane with the other …
An IonStar experimental strategy for MS1 ion current-based quantification using ultrahigh-field orbitrap: reproducible, in-depth, and accurate protein measurement in …
In-depth and reproducible protein measurement in many biological samples is often critical
for pharmaceutical/biomedical proteomics but remains challenging. MS1-based …
for pharmaceutical/biomedical proteomics but remains challenging. MS1-based …
The story of protein arginine methylation: characterization, regulation, and function
C Peng, CCL Wong - Expert Review of Proteomics, 2017 - Taylor & Francis
Introduction: Arginine methylation is an important post-translational modification (PTM) in
cells, which is catalyzed by a group of protein arginine methyltransferases (PRMTs). It plays …
cells, which is catalyzed by a group of protein arginine methyltransferases (PRMTs). It plays …
[HTML][HTML] Large scale mass spectrometry-based identifications of enzyme-mediated protein methylation are subject to high false discovery rates
All large scale LC-MS/MS post-translational methylation site discovery experiments require
methylpeptide spectrum matches (methyl-PSMs) to be identified at acceptably low false …
methylpeptide spectrum matches (methyl-PSMs) to be identified at acceptably low false …
The Alba protein family: Structure and function
Alba family proteins are small, basic, dimeric nucleic acid-binding proteins, which are widely
distributed in archaea and a number of eukaryotes. This family of proteins bears the distinct …
distributed in archaea and a number of eukaryotes. This family of proteins bears the distinct …
Emerging technologies to map the protein methylome
Protein methylation plays an integral role in cellular signaling, most notably by modulating
proteins bound at chromatin and increasingly through regulation of non-histone proteins …
proteins bound at chromatin and increasingly through regulation of non-histone proteins …