Periodontitis is a chronic infectious disorder damaging periodontal tissues, including the
gingiva, periodontal ligament, cementum, and alveolar bone. It arises from the complex …

Bone tissue in vertebrates is essential to performing movements, to protecting internal
organs and to regulating calcium homeostasis. Moreover, bone has also been suggested to …

Patients with diabetes often experience fragile fractures despite normal or higher bone
mineral density (BMD), a phenomenon termed the diabetic bone paradox (DBP). The …

Background With the deepening of social aging, the incidence rate of osteoporosis and
diabetes continues to rise. More and more clinical studies show that diabetes is highly …

Hydroxyapatite, an essential mineral in human bones composed mainly of calcium and
phosphorus, is widely used to coat bone graft and implant surfaces for enhanced …

Patients with type 2 diabetes have an increased risk of fracture compared to the general
population. Glucose absorption is accelerated by incretin hormones, which induce insulin …

Bone is increasingly recognized as a target for diabetic complications. In order to evaluate
the direct effects of high glucose on bone, we investigated the global transcriptional changes …

Bone defects present significant clinical challenges in orthopedics, orthodontics, and
maxillofacial surgeries. Accelerated bone regeneration can be facilitated by incorporating …

Abstract Purpose of Review Obesity is highly prevalent and is associated with bone fragility
and fracture. The changing nutrient availability to bone in obesity is an important facet of …

Mitochondria play a crucial role in cell physiology and pathophysiology. In this context,
mitochondrial dynamics and, subsequently, mitochondrial ultrastructure have increasingly …