Importance The incidence of early-onset colorectal cancer (younger than 50 years) is rising
globally, the reasons for which are unclear. It appears to represent a unique disease …

Over the past several decades, the incidence of early-onset colorectal cancer (EOCRC; in
patients< 50 years old) has increased at an alarming rate. Although robust and scientifically …

Treatment of young adults with colorectal cancer (CRC) represents an unmet clinical need,
especially as diagnosis in this population might lead to the greatest loss of years of life …

Abstract Each year, the American Cancer Society publishes a summary of its guidelines for
early cancer detection, data and trends in cancer screening rates from the National Health …

Sporadic colorectal cancer has traditionally been viewed as a malignancy of older
individuals. However, as the global prevalence of the disease diagnosed in younger …

Importance Colorectal cancer (CRC) incidence and mortality among individuals younger
than 50 years (early-onset CRC) are increasing. The reasons for such increases are largely …

Colorectal cancer (CRC) incidence rates in the United States overall have declined since
the mid-1980s because of changing patterns in risk factors (eg, decreased smoking) and …

Background The causative factors for the recent increase in early-onset colorectal cancer
(EO-CRC) incidence are unknown. We sought to determine if early-onset disease is …

Background Colorectal cancer (CRC) incidence is increasing in adults younger than 50
years. This study evaluated clinical and molecular features to identify those features unique …

Purpose: The incidence rates of colorectal cancers are increasing in young adults. The
objective of this study was to investigate genomic differences between tumor samples …