Tumor-induced osteomalacia: a comprehensive review
Tumor-induced osteomalacia (TIO) is an ultrarare paraneoplastic syndrome due to
overproduction of fibroblast growth factor 23 (FGF23), with profound effects on patient …
overproduction of fibroblast growth factor 23 (FGF23), with profound effects on patient …
FGF23 and its role in X-linked hypophosphatemia-related morbidity
Background X-linked hypophosphatemia (XLH) is an inherited disease of phosphate
metabolism in which inactivating mutations of the Phosphate Regulating Endopeptidase …
metabolism in which inactivating mutations of the Phosphate Regulating Endopeptidase …
Tumour-induced osteomalacia
S Minisola, M Peacock, S Fukumoto… - Nature reviews Disease …, 2017 - nature.com
Abstract Tumour-induced osteomalacia (TIO), also known as oncogenic osteomalacia, is a
rare paraneoplastic disorder caused by tumours that secrete fibroblast growth factor 23 …
rare paraneoplastic disorder caused by tumours that secrete fibroblast growth factor 23 …
Tumor-induced osteomalacia
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by tumoral
production of fibroblast growth factor 23 (FGF23). The hallmark biochemical features include …
production of fibroblast growth factor 23 (FGF23). The hallmark biochemical features include …
Tumor-induced osteomalacia: a systematic clinical review of 895 cases
A Bosman, A Palermo, J Vanderhulst… - Calcified tissue …, 2022 - Springer
Tumor-induced osteomalacia (TIO) is a rare and largely underdiagnosed paraneoplastic
condition. Previous reviews often reported incomplete data on clinical aspects, diagnosis or …
condition. Previous reviews often reported incomplete data on clinical aspects, diagnosis or …
Physiological regulation of phosphate by vitamin D, parathyroid hormone (PTH) and phosphate (Pi)
G Jacquillet, RJ Unwin - Pflügers Archiv-European Journal of Physiology, 2019 - Springer
Inorganic phosphate (Pi) is an abundant element in the body and is essential for a wide
variety of key biological processes. It plays an essential role in cellular energy metabolism …
variety of key biological processes. It plays an essential role in cellular energy metabolism …
The PTH-vitamin d-FGF23 axis
JE Blau, MT Collins - Reviews in Endocrine and Metabolic Disorders, 2015 - Springer
Abstract Fibroblast growth factor 23 (FGF23) has emerged as an important regulator of
phosphate and vitamin D homeostasis. It is important to understand how FGF23 interacts …
phosphate and vitamin D homeostasis. It is important to understand how FGF23 interacts …
Tumor‐induced osteomalacia: an important cause of adult‐onset hypophosphatemic osteomalacia in China: report of 39 cases and review of the literature
Y Jiang, W **a, X **ng, BC Silva, M Li… - Journal of Bone and …, 2012 - academic.oup.com
Tumor‐induced osteomalacia (TIO) is an acquired form of hypophosphatemia. Tumor
resection leads to cure. We investigated the clinical characteristics of TIO, diagnostic …
resection leads to cure. We investigated the clinical characteristics of TIO, diagnostic …
Interim analysis of a phase 2 open‐label trial assessing burosumab efficacy and safety in patients with tumor‐induced osteomalacia
Patients with tumor‐induced osteomalacia (TIO), an acquired paraneoplastic condition
characterized by osteomalacia due to hypophosphatemia, exhibit a similar clinical picture to …
characterized by osteomalacia due to hypophosphatemia, exhibit a similar clinical picture to …
X-linked hypophosphatemia and FGF23-related hypophosphatemic diseases: prospect for new treatment
Y Kinoshita, S Fukumoto - Endocrine reviews, 2018 - academic.oup.com
Phosphate plays essential roles in many biological processes, and the serum phosphate
level is tightly controlled. Chronic hypophosphatemia causes impaired mineralization of the …
level is tightly controlled. Chronic hypophosphatemia causes impaired mineralization of the …