Extending thrombolysis to 4· 5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data

BCV Campbell, H Ma, PA Ringleb, MW Parsons… - The Lancet, 2019 - thelancet.com
Background Stroke thrombolysis with alteplase is currently recommended 0–4· 5 h after
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …

Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a …

BCV Campbell, CBLM Majoie, GW Albers… - The Lancet …, 2019 - thelancet.com
Background CT perfusion (CTP) and diffusion or perfusion MRI might assist patient selection
for endovascular thrombectomy. We aimed to establish whether imaging assessments of …

Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke

H Ma, BCV Campbell, MW Parsons… - … England Journal of …, 2019 - Mass Medical Soc
Background The time to initiate intravenous thrombolysis for acute ischemic stroke is
generally limited to within 4.5 hours after the onset of symptoms. Some trials have suggested …

Endovascular therapy for ischemic stroke with perfusion-imaging selection

BCV Campbell, PJ Mitchell, TJ Kleinig… - … England Journal of …, 2015 - Mass Medical Soc
Background Trials of endovascular therapy for ischemic stroke have produced variable
results. We conducted this study to test whether more advanced imaging selection, recently …

Prevalence and significance of impaired microvascular tissue reperfusion despite macrovascular angiographic reperfusion (no-reflow)

FC Ng, L Churilov, N Yassi, TJ Kleinig, V Thijs, T Wu… - Neurology, 2022 - neurology.org
Background and Objectives The relevance of impaired microvascular tissue-level
reperfusion despite complete upstream macrovascular angiographic reperfusion (no-reflow) …

Multiphase CT angiography: a new tool for the imaging triage of patients with acute ischemic stroke

BK Menon, CD d'Esterre, EM Qazi, M Almekhlafi… - Radiology, 2015 - pubs.rsna.org
Purpose To describe the use of an imaging selection tool, multiphase computed
tomographic (CT) angiography, in patients with acute ischemic stroke (AIS) and to …

Current practice and future directions in the diagnosis and acute treatment of ischaemic stroke

C Zerna, G Thomalla, BCV Campbell, JH Rha, MD Hill - The Lancet, 2018 - thelancet.com
Even though stroke presents as a variety of clinical syndromes, neuroimaging is the most
important biomarker to help differentiate between stroke subtypes and assess treatment …

Automated CT perfusion imaging for acute ischemic stroke: pearls and pitfalls for real-world use

A Vagal, M Wintermark, K Nael, A Bivard, M Parsons… - Neurology, 2019 - neurology.org
Recent positive trials have thrust acute cerebral perfusion imaging into the routine
evaluation of acute ischemic stroke. Updated guidelines state that in patients with anterior …

Multimodal predictive modeling of endovascular treatment outcome for acute ischemic stroke using machine-learning

G Brugnara, U Neuberger, MA Mahmutoglu, M Foltyn… - Stroke, 2020 - ahajournals.org
Background and Purpose: This study assessed the predictive performance and relative
importance of clinical, multimodal imaging, and angiographic characteristics for predicting …

Brain ischemia: CT and MRI techniques in acute ischemic stroke

P Vilela, HA Rowley - European journal of radiology, 2017 - Elsevier
Imaging plays a central role for intravenous and intra-arterial arterial ischemic stroke
treatment patient selection. Computed tomography (CT)/CT angiography or magnetic …