Catalysis and Electron Transfer in De Novo Designed Metalloproteins

KJ Koebke, TBJ Pinter, WC Pitts, VL Pecoraro - Chemical reviews, 2022‏ - ACS Publications
One of the hallmark advances in our understanding of metalloprotein function is showcased
in our ability to design new, non-native, catalytically active protein scaffolds. This review …

Bionanomaterials based on protein self-assembly: Design and applications in biotechnology

R Zeng, C Lv, C Wang, G Zhao - Biotechnology Advances, 2021‏ - Elsevier
Elegant protein assembly to generate new biomaterials undergoes extremely rapid
development for wide extension of biotechnology applications, which can be a powerful tool …

Tuning the Chirality Evolution in Achiral Subnanometer Systems by Judicious Control of Molecule Interactions

Q Liu, Z Sheng, W Shi, X Cheng, X Xu… - Journal of the American …, 2024‏ - ACS Publications
Chirality evolution from molecule levels to the nanoscale in an achiral system is a
fundamental issue that remains undiscovered. Here, we report the assembly of …

Tunable circularly polarized luminescence from single crystal and powder of the simplest tetraphenylethylene helicate

M Hu, FY Ye, C Du, W Wang, TT Zhou, ML Gao, M Liu… - ACS …, 2021‏ - ACS Publications
Tetraphenylethylene and its derivatives are a class of aggregation-induced emission (AIE)
compounds that are most extensively and successfully studied. It has been found that the …

Thermoresponsive Micellar Assembly Constructed from a Hexameric Hemoprotein Modified with Poly(N-isopropylacrylamide) toward an Artificial Light-Harvesting …

S Hirayama, K Oohora, T Uchihashi… - Journal of the American …, 2020‏ - ACS Publications
Artificial protein assemblies inspired by nature have significant potential in development of
emergent functional materials. In order to construct an artificial protein assembly, we …

An expandable, modular de novo protein platform for precision redox engineering

GH Hutchins, CEM Noble, HA Bunzel… - Proceedings of the …, 2023‏ - pnas.org
The electron-conducting circuitry of life represents an as-yet untapped resource of exquisite,
nanoscale biomolecular engineering. Here, we report the characterization and structure of a …

A bionanozyme with ultrahigh activity enables spatiotemporally controlled reactive oxygen species generation for cancer therapy

Z Xu, L Zhang, M Pan, Q Jiang, Y Huang… - Advanced Functional …, 2021‏ - Wiley Online Library
Nanozymes hold great potential in nanomedicine, yet biotoxicity limits their clinical
translation because of their uncontrolled catalytic activity, artificial inorganic components …

Allosteric cooperation in a de novo-designed two-domain protein

F Pirro, N Schmidt, J Lincoff, ZX Widel… - Proceedings of the …, 2020‏ - pnas.org
We describe the de novo design of an allosterically regulated protein, which comprises two
tightly coupled domains. One domain is based on the DF (Due Ferri in Italian or two-iron in …

Hierarchical self-assembly of proteins through rationally designed supramolecular interfaces

H Sun, Y Li, S Yu, J Liu - Frontiers in Bioengineering and …, 2020‏ - frontiersin.org
With the increasing advances in the basic understanding of pathogenesis mechanism and
fabrication of advanced biological materials, protein nanomaterials are being developed for …

Formation of β-lactoglobulin self-assemblies via liquid–liquid phase separation for applications beyond the biological functions

TD Zhang, X Deng, MY Wang, LL Chen… - … Applied Materials & …, 2021‏ - ACS Publications
Proteins are like miracle machines, playing important roles in living organisms. They perform
vital biofunctions by further combining together and/or with other biomacromolecules to form …