Immune-mediated inflammatory diseases (IMIDs) are characterized by excessive and
uncontrolled inflammation and thrombosis, both of which are responsible for organ damage …

Platelets are anucleate cells that are crucial mediators of haemostasis. Most immunologists
probably don't think about platelets every day, and may even consider these cells to …

Platelet-rich plasma (PRP) has been utilized in surgery for 2 decades; there has been a
recent interest in the use of PRP for the treatment of sports-related injuries. PRP contains …

Platelets are known for their role in haemostasis where they help prevent blood loss at sites
of vascular injury. To do this, they adhere, aggregate and form a procoagulant surface …

Antimicrobial peptides (AMPs) are short peptidic molecules produced by most living
creatures. They help unicellular organisms to successfully compete for nutrients with other …

α-Granules are essential to normal platelet activity. These unusual secretory granules derive
their cargo from both regulated secretory and endocytotic pathways in megakaryocytes …

Blood platelets have long been recognised to bring about primary haemostasis with
deficiencies in platelet production and function manifesting in bleeding while upregulated …

Platelets are the primary cellular mediators of hemostasis and this function firmly acquaints
them with a variety of inflammatory processes. For example, platelets can act as circulating …

The production of peptides and small proteins with microbicidal activity collectively called
antimicrobial peptides (AMPs) is commonly considered to be a primitive mechanism of …

Beyond an eminent role in hemostasis and thrombosis, platelets are characterized by expert
functions in assisting and modulating inflammatory reactions and immune responses. This is …