During embryogenesis, organs undergo dynamic shape transformations that sculpt their
final shape, composition, and function. Despite this, current organ bioprinting approaches …

The human heart beats as a result of multiscale nonlinear dynamics coupling subcellular to
whole organ processes, achieving electrophysiologically-driven mechanical contraction …

Auxetic behaviour, the unphysical transverse expansion during uniaxial tension, is a
common and undesirable feature of classical anisotropic hyperelastic constitutive models for …

Single ventricle patients, including those with hypoplastic left heart syndrome (HLHS),
typically undergo three palliative heart surgeries culminating in the Fontan procedure. HLHS …

Myocardial infarction (MI) rapidly impairs cardiac contractile function and instigates
maladaptive remodeling leading to heart failure. Patient-specific models are a maturing …

Myocardium passive mechanical response has been a major topic of study for decades due
to its major impact on cardiac physiology. Here, we propose a novel modeling methodology …

The finite element method (FEM) is commonly used in computational cardiac simulations.
For this method, a mesh is constructed to represent the geometry and, subsequently, to …

Constitutive laws that describe the mechanical responses of cardiac tissue under loading
hold the key to accurately model the biomechanical behaviour of the heart. There have been …

Mechanical thrombectomy can be significantly affected by the mechanical properties of the
occluding thrombus. In this study, we provide the first characterisation of the volumetric …

Traditional mechanical characterization of extremely soft tissues is challenging given
difficulty extracting tissue, satisfying geometric requirements, kee** tissues hydrated, and …