In this review we examine the effects of both over-and under-production of heme oxygenase-
1 (HO-1) and HO activity on a broad spectrum of biological systems and on vascular …

The global epidemic of obesity continues unabated with sequelae of diabetes and metabolic
syndrome. This review reflects the dramatic increase in research on the role of increased …

Carbon monoxide (CO) is a gasotransmitter that plays important roles in regulating cell
functions and has shown therapeutic effects in clinic studies. CO releasing molecules …

Along with the impressive achievements in understanding the endogenous signaling roles
and mechanism (s) of action of carbon monoxide (CO), much research has demonstrated …

Carbon monoxide (CO) is a ubiquitously produced endogenous gas in mammalian cells and
is involved in stress response being considered as a cytoprotective and homeostatic factor …

Dietary factors influence male reproductive function in both experimental and
epidemiological studies. However, there are currently no specific dietary guidelines for male …

Carbon monoxide (CO) has long been known as the “silent killer” owing to its ability to form
carboxyhemoglobin—the main cause of CO poisoning in humans. Its role as an …

Carbon monoxide (CO) is a gasotransmitter endogenously produced by the activity of heme
oxygenase, which is a stress-response enzyme. Endogenous CO or low concentrations of …

Biliverdin reductase (BVR) is an enzymatic and signaling protein that has multifaceted roles
in physiological systems. Despite the wealth of knowledge about BVR, no data exist …

Aims/hypothesis Iron excess in adipose tissue is known to promote adipose tissue
dysfunction. Here, we aimed to investigate the possible role of haem oxygenase 1 (HMOX1) …