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Studying and modelling dynamic biological processes using time-series gene expression data
Biological processes are often dynamic, thus researchers must monitor their activity at
multiple time points. The most abundant source of information regarding such dynamic …
multiple time points. The most abundant source of information regarding such dynamic …
[HTML][HTML] HRP2: transforming malaria diagnosis, but with caveats
The major growth in point-of-care malaria diagnosis over the past decade has been based
on immunochromatographic malaria rapid diagnostic tests (mRDTs), which generally detect …
on immunochromatographic malaria rapid diagnostic tests (mRDTs), which generally detect …
Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis
INTRODUCTION Malaria remains a devastating global parasitic disease, with the majority of
malaria deaths caused by the highly virulent Plasmodium falciparum. The extreme AT-bias …
malaria deaths caused by the highly virulent Plasmodium falciparum. The extreme AT-bias …
Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data
Motivation: High-throughput sequencing (HTS) technologies have made low-cost
sequencing of large numbers of samples commonplace. An explosion in the type, not just …
sequencing of large numbers of samples commonplace. An explosion in the type, not just …
Integrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression
E Lasonder, SR Rijpma, BCL van Schaijk… - Nucleic acids …, 2016 - academic.oup.com
Sexual differentiation of malaria parasites into gametocytes in the vertebrate host and
subsequent gamete fertilization in mosquitoes is essential for the spreading of the disease …
subsequent gamete fertilization in mosquitoes is essential for the spreading of the disease …
Lignin metabolism has a central role in the resistance of cotton to the wilt fungus Verticillium dahliae as revealed by RNA-Seq-dependent transcriptional analysis and …
The incompatible pathosystem between resistant cotton (Gossypium barbadense cv. 7124)
and Verticillium dahliae strain V991 was used to study the cotton transcriptome changes …
and Verticillium dahliae strain V991 was used to study the cotton transcriptome changes …
A Systematically Improved High Quality Genome and Transcriptome of the Human Blood Fluke Schistosoma mansoni
Schistosomiasis is one of the most prevalent parasitic diseases, affecting millions of people
in develo** countries. Amongst the human-infective species, Schistosoma mansoni is also …
in develo** countries. Amongst the human-infective species, Schistosoma mansoni is also …
Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites
Single-cell RNA-sequencing is revolutionising our understanding of seemingly
homogeneous cell populations but has not yet been widely applied to single-celled …
homogeneous cell populations but has not yet been widely applied to single-celled …
[HTML][HTML] Chromatin accessibility-based characterization of the gene regulatory network underlying Plasmodium falciparum blood-stage development
CG Toenhake, SAK Fraschka, MS Vijayabaskar… - Cell host & …, 2018 - cell.com
Underlying the development of malaria parasites within erythrocytes and the resulting
pathogenicity is a hardwired program that secures proper timing of gene transcription and …
pathogenicity is a hardwired program that secures proper timing of gene transcription and …
Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum
Background It has been shown that nearly a quarter of the initial predicted gene models in
the Plasmodium falciparum genome contain errors. Although there have been efforts to …
the Plasmodium falciparum genome contain errors. Although there have been efforts to …