In-cell NMR: Why and how?

FX Theillet, E Luchinat - Progress in Nuclear Magnetic Resonance …, 2022 - Elsevier
NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …

Cerebral oxygen extraction fraction MRI: Techniques and applications

D Jiang, H Lu - Magnetic resonance in medicine, 2022 - Wiley Online Library
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

Reduced global cerebral oxygen metabolic rate in sickle cell disease and chronic anemias

C Vu, A Bush, S Choi, M Borzage… - American journal of …, 2021 - Wiley Online Library
Anemia is the most common blood disorder in the world. In patients with chronic anemia,
such as sickle cell disease or major thalassemia, cerebral blood flow increases to …

Normalization of cerebral hemodynamics after hematopoietic stem cell transplant in children with sickle cell disease

ML Hulbert, ME Fields, KP Guilliams, P Bijlani… - Blood, 2023 - ashpublications.org
Children with sickle cell disease (SCD) demonstrate cerebral hemodynamic stress and are
at high risk of strokes. We hypothesized that curative hematopoietic stem cell transplant …

Iron in blood cells: Function, relation to disease, and potential for magnetic separation

S Barua, S Ciannella, L Tijani… - Biotechnology and …, 2023 - Wiley Online Library
Iron in blood cells has several physiological functions like transporting oxygen to cells and
maintaining iron homeostasis. Iron is primarily contained in red blood cells (RBCs), but …

Cerebral hemodynamic changes after haploidentical hematopoietic stem cell transplant in adults with sickle cell disease

MA Aumann, W Richerson, AK Song, LT Davis… - Blood …, 2024 - ashpublications.org
Preliminary evidence from a series of 4 adults with sickle cell disease (SCD) suggests that
hematopoietic stem cell transplant (HSCT) improves cerebral hemodynamics. HSCT largely …

The unique magnetic signature of sickle red blood cells: a comparison between the red blood cells of transfused and non-transfused sickle cell disease patients and …

M Weigand, J Gomez-Pastora, J Strayer… - IEEE Transactions …, 2022 - ieeexplore.ieee.org
Sickle cell disease (SCD) is an inherited blood disorder that affects millions of people
worldwide, especially in low-resource regions of the world, where a rapid and affordable test …

[HTML][HTML] Continuous-flow magnetic fractionation of red blood cells based on hemoglobin content and oxygen saturation—clinical blood supply implications and sickle …

M Weigand, J Gomez-Pastora, A Palmer, M Zborowski… - Processes, 2022 - mdpi.com
Processes | Free Full-Text | Continuous-Flow Magnetic Fractionation of Red Blood Cells Based
on Hemoglobin Content and Oxygen Saturation—Clinical Blood Supply Implications …

Anemia increases oxygen extraction fraction in deep brain structures but not in the cerebral cortex

J Shen, X Miao, C Vu, B Xu… - Frontiers in …, 2022 - frontiersin.org
Sickle cell disease (SCD) is caused by a single amino acid mutation in hemoglobin, causing
chronic anemia and neurovascular complications. However, the effects of chronic anemia on …

Increased White Matter Aerobic Glycolysis in Multiple Sclerosis

MR Brier, B Judge, C Ying, A Salter, H An… - Annals of …, 2024 - Wiley Online Library
Objective Despite treatments which reduce relapses in multiple sclerosis (MS), many
patients continue to experience progressive disability accumulation. MS is associated with …