Counterattacking the tick bite: towards a rational design of anti-tick vaccines targeting pathogen transmission

ROM Rego, JJA Trentelman, J Anguita, AM Nijhof… - Parasites & vectors, 2019 - Springer
Hematophagous arthropods are responsible for the transmission of a variety of pathogens
that cause disease in humans and animals. Ticks of the Ixodes ricinus complex are vectors …

A high-quality Ixodes scapularis genome advances tick science

S De, SB Kingan, C Kitsou, DM Portik, SD Foor… - Nature Genetics, 2023 - nature.com
Ixodes spp. and related ticks transmit prevalent infections, although knowledge of their
biology and development of anti-tick measures have been hindered by the lack of a high …

Universal tick vaccines: candidates and remaining challenges

LF Parizi, NW Githaka, C Logullo, J Zhou, M Onuma… - Animals, 2023 - mdpi.com
Simple Summary Various new technologies have been used to learn more about tick
physiology and biology in hopes of develo** vaccines to protect people and animals from …

The Bm86 discovery: a revolution in the development of anti-tick vaccines

A Rodríguez-Mallon - Pathogens, 2023 - mdpi.com
The presence in nature of species with genetic resistance to ticks, or with acquired
resistance after repeated tick infestations, has encouraged the scientific community to …

What do we know about the microbiome of I. ricinus?

R Hodosi, M Kazimirova, K Soltys - Frontiers in cellular and infection …, 2022 - frontiersin.org
I. ricinus is an obligate hematophagous parasitic arthropod that is responsible for the
transmission of a wide range of zoonotic pathogens including spirochetes of the genus …

[HTML][HTML] A multi-omics approach for understanding blood digestion dynamics in Ixodes scapularis and identification of anti-tick vaccine targets

JB Reyes, M McVicar, S Beniwal, A Sharma… - Ticks and tick-borne …, 2024 - Elsevier
Ixodes scapularis, the black-legged tick, is a major arthropod vector that transmits the
causative agents of Lyme disease and several other pathogens of human significance. The …

Past, present, and future of Lyme disease vaccines: antigen engineering approaches and mechanistic insights

WH Chen, U Strych, ME Bottazzi… - Expert review of vaccines, 2022 - Taylor & Francis
ABSTRACT Introduction Transmitted by ticks, Lyme disease is the most common vector-
borne disease in the Northern hemisphere. Despite the geographical expansion of human …

Human tick-borne diseases and advances in anti-tick vaccine approaches: a comprehensive review

ME Nepveu-Traversy, H Fausther-Bovendo… - Vaccines, 2024 - mdpi.com
This comprehensive review explores the field of anti-tick vaccines, addressing their
significance in combating tick-borne diseases of public health concern. The main objectives …

Identification and Characterization of Rhipicephalus microplus ATAQ Homolog from Haemaphysalis longicornis Ticks and Its Immunogenic Potential as an Anti-Tick …

PF Adjou Moumouni, S Naomasa, B Tuvshintulga… - Microorganisms, 2023 - mdpi.com
Although vaccines are one of the environmentally friendly means to prevent the spread of
ticks, there is currently no commercial vaccine effective against Haemaphysalis longicornis …

Identification and Characterization of Immunodominant Proteins from Tick Tissue Extracts Inducing a Protective Immune Response against Ixodes ricinus in Cattle

S Knorr, S Reissert-Oppermann, J Tomás-Cortázar… - Vaccines, 2021 - mdpi.com
Ixodes ricinus is the main vector of tick-borne diseases in Europe. An immunization trial of
calves with soluble extracts of I. ricinus salivary glands (SGE) or midgut (ME) previously …