Reactive oxygen species (ROS) mediate lipid peroxidation and produce 4-hydroxynonenal
and other related products, which play an important role in the process of cell death …

Ferroptosis offers a novel method for overcoming therapeutic resistance of cancers to
conventional cancer treatment regimens. Its effective use as a cancer therapy requires a …

Background Drug resistance to sorafenib greatly limited the benefits of treatment in patients
with hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) participate in the development …

Microplastics (MPs), which are emerging environmental pollutants, remain uncertainties in
their toxic mechanism. MPs have been linked to severe liver metabolic disorders and …

Activation of hepatic stellate cells (HSCs) is a central event in the development of liver
fibrosis, and the elimination of activated HSCs is considered to be an effective anti-fibrotic …

Reactive oxygen species (ROS) play a crucial part in the process of cell death, including
apoptosis, autophagy, and ferroptosis. ROS involves in the oxidation of lipids and generate …

Ferroptosis, featuring an iron‐dependent peroxidation of lipids, is a novel form of
programmed cell death that may hold great potential in cancer therapy. Our study found that …

Parkinson's disease (PD) is a progressive nervous system disorder. Until now, the molecular
mechanism of its occurrence is not fully understood. Paraquat (PQ) was identified as a …

Abstract Thymosin beta 4 (Tβ4) can improve the liver fibrosis and reduce inflammation, while
the role of Tβ4 in non-alcoholic fatty liver disease (NAFLD) whether mediated by ferroptosis …

Isoniazid (INH) and rifampicin (RFP) are the first-line medications for tuberculosis treatment,
and liver injury is the major adverse effect. Natural medicinal ingredients provide distinct …