Timing of lifespan influences on brain and cognition
Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …
Modeling prenatal opioid exposure in animals: current findings and future directions
The past decade has seen a drastic rise in the number of infants exposed to opioids in utero.
It is unclear what lasting effect this exposure may have on these children. Animal models of …
It is unclear what lasting effect this exposure may have on these children. Animal models of …
Prenatal opioid exposure: the next neonatal neuroinflammatory disease
LL Jantzie, JR Maxwell, JC Newville… - Brain, behavior, and …, 2020 - Elsevier
The rates of opioid use disorder during pregnancy have more than quadrupled in the last
decade, resulting in numerous infants suffering exposure to opioids during the perinatal …
decade, resulting in numerous infants suffering exposure to opioids during the perinatal …
Neonatal abstinence syndrome
M Grossman, A Berkwitt - Seminars in perinatology, 2019 - Elsevier
Neonates exposed prenatally to opioids will often develop a collection of withdrawal signs
known as neonatal abstinence syndrome (NAS). The incidence of NAS has substantially …
known as neonatal abstinence syndrome (NAS). The incidence of NAS has substantially …
Clinical and basic research investigations into the long‐term effects of prenatal opioid exposure on brain development
T Boggess, WC Risher - Journal of neuroscience research, 2022 - Wiley Online Library
Coincident with the opioid epidemic in the United States has been a dramatic increase in the
number of children born with neonatal abstinence syndrome (NAS), a form of withdrawal …
number of children born with neonatal abstinence syndrome (NAS), a form of withdrawal …
Buprenorphine compared with methadone in pregnancy: a systematic review and meta-analysis
M Kinsella, LOE Halliday, M Shaw, Y Capel… - Substance Use & …, 2022 - Taylor & Francis
Introduction Illicit opioid use in pregnancy is associated with adverse maternal, neonatal,
and childhood outcomes. Opioid substitution is recommended, but whether methadone or …
and childhood outcomes. Opioid substitution is recommended, but whether methadone or …
Opioid use in pregnancy
Abstract Purpose of Review Perinatal opioid use is a major public health problem and is
associated with a number of deleterious maternal and fetal effects. We review recent …
associated with a number of deleterious maternal and fetal effects. We review recent …
Perinatal morphine exposure leads to sex-dependent executive function deficits and microglial changes in mice
Children exposed prenatally to opioids are at an increased risk for behavioral problems and
executive function deficits. The prefrontal cortex (PFC) and amygdala (AMG) regulate …
executive function deficits. The prefrontal cortex (PFC) and amygdala (AMG) regulate …
Prenatal opioid exposure and vulnerability to future substance use disorders in offspring
Y Abu, S Roy - Experimental neurology, 2021 - Elsevier
The heightened incidence of opioid use during pregnancy has resulted in unprecedented
rates of neonates prenatally exposed to opioids. Prenatal opioid exposure (POE) results in …
rates of neonates prenatally exposed to opioids. Prenatal opioid exposure (POE) results in …
Effects of prenatal opioid exposure on synaptic adaptations and behaviors across development
In this review, we focus on prenatal opioid exposure (POE) given the significant concern for
the mental health outcomes of children with parents affected by opioid use disorder (OUD) in …
the mental health outcomes of children with parents affected by opioid use disorder (OUD) in …