Cytochrome c oxidase in animals, plants and many aerobic bacteria functions as the
terminal enzyme of the respiratory chain where it reduces molecular oxygen to form water in …

One of the current aims of synthetic biology is the development of novel microorganisms that
can mine economically important elements from the environment or remediate toxic waste …

Ammonia-oxidizing archaea (AOA) are widespread in nature and are involved in nitrification,
an essential process in the global nitrogen cycle. The enzymes for ammonia oxidation and …

Corynebacterium glutamicum is a preferentially aerobic gram-positive bacterium belonging
to the phylum Actinobacteria, which also includes the pathogen Mycobacterium tuberculosis …

The aromatic heterocyclic compound indole is widely spread in nature. Due to its floral odor
indole finds application in dairy, flavor, and fragrance products. Indole is an inter-and …

Heme is a multifaceted molecule. While serving as a prosthetic group for many important
proteins, elevated levels are toxic to cells. The complexity of this stimulus has shaped …

Bacteria require a precise balance of copper ions to ensure that essential cuproproteins are
fully metalated while also avoiding copper-induced toxicity. The Gram-positive bacterium …

Copper (Cu) is an essential, but toxic, micronutrient for living organisms and cells have
developed sophisticated response mechanisms towards both the lack and the excess of Cu …

The di‐copper center CuA is an essential metal cofactor in cytochrome oxidase (Cox) of
mitochondria and many prokaryotes, mediating one‐electron transfer from cytochrome c to …

Respiration in aerobic Actinobacteria involves a cytochrome bc 1-aa 3 supercomplex with a
diheme cytochrome c 1, first isolated from Corynebacterium glutamicum. Synthesis of a …