Immunosuppressive agents in solid organ transplantation: Mechanisms of action and therapeutic efficacy
AL Taylor, CJE Watson, JA Bradley - Critical reviews in oncology …, 2005 - Elsevier
Effective immunosuppression is an essential pre-requisite for successful organ
transplantation and improvements in outcome after transplantation have to a large extent …
transplantation and improvements in outcome after transplantation have to a large extent …
Industrial natural product chemistry for drug discovery and development
A Bauer, M Brönstrup - Natural product reports, 2014 - pubs.rsc.org
Covering: up to March 2013 In addition to their prominent role in basic biological and
chemical research, natural products are a rich source of commercial products for the …
chemical research, natural products are a rich source of commercial products for the …
[KÖNYV][B] Diseases of the liver and biliary system
S Sherlock, J Dooley - 2002 - Wiley Online Library
Bilirubin metabolism, 205 Hepatic transport and conjugation of bilirubin, 205 Distribution of
jaundice in the tissues, 207 Factors determining the depth of jaundice, 207 Classification of …
jaundice in the tissues, 207 Factors determining the depth of jaundice, 207 Classification of …
Immunosuppression in liver transplant
T Di Maira, EC Little, M Berenguer - Best Practice & Research Clinical …, 2020 - Elsevier
The increasing potency of immunosuppression (IS) agents resulted in significantly
decreased rates of steroid resistant rejection and rejection related graft loss in liver …
decreased rates of steroid resistant rejection and rejection related graft loss in liver …
[HTML][HTML] Pediatric liver transplantation
M Spada, S Riva, G Maggiore, D Cintorino… - World journal of …, 2009 - ncbi.nlm.nih.gov
In previous decades, pediatric liver transplantation has become a state-of-the-art operation
with excellent success and limited mortality. Graft and patient survival have continued to …
with excellent success and limited mortality. Graft and patient survival have continued to …
Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients
JD Morrisett, G Abdel-Fattah, R Hoogeveen… - Journal of lipid …, 2002 - ASBMB
Sirolimus (Rapammune®, rapamycin, RAPA) is a potent immunosuppressive drug that
reduces renal transplant rejection. Hyperlipidemia is a significant side effect of sirolimus …
reduces renal transplant rejection. Hyperlipidemia is a significant side effect of sirolimus …
mTOR-related brain dysfunctions in neuropsychiatric disorders
The mammalian target of rapamycin (mTOR) is an ubiquitously expressed serine-threonine
kinase, which senses and integrates several intracellular and environmental cues to …
kinase, which senses and integrates several intracellular and environmental cues to …
[PDF][PDF] Sirolimus‐based immunosuppression for liver transplantation in the presence of extended criteria for hepatocellular carcinoma
An increasing number of patients with hepatocellular carcinoma (HCC) are undergoing
evaluation for listing for liver transplantation. Criteria for selection require ongoing review for …
evaluation for listing for liver transplantation. Criteria for selection require ongoing review for …
Sirolimus-tacrolimus combination immunosuppression
Sirolimus-tacrolimus combination immunosuppression - The Lancet Skip to Main Content
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[PDF][PDF] Sirolimus‐based immunosuppression following liver transplantation for hepatocellular carcinoma
Experience with sirolimus (SRL)‐based immunosuppression following orthotopic liver
transplantation (OLT) is rapidly accumulating. In combination with calcineurin inhibitors …
transplantation (OLT) is rapidly accumulating. In combination with calcineurin inhibitors …