Cholesterol, sphingolipids, and glycolipids: what do we know about their role in raft-like membranes?

T Róg, I Vattulainen - Chemistry and physics of lipids, 2014 - Elsevier
Lipids rafts are considered to be functional nanoscale membrane domains enriched in
cholesterol and sphingolipids, characteristic in particular of the external leaflet of cell …

Effects of nitro-oxidative stress on biomolecules: part 1—non-reactive molecular dynamics simulations

M Ghasemitarei, T Ghorbi, M Yusupov, Y Zhang… - Biomolecules, 2023 - mdpi.com
Plasma medicine, or the biomedical application of cold atmospheric plasma (CAP), is an
expanding field within plasma research. CAP has demonstrated remarkable versatility in …

[HTML][HTML] An overview of molecular dynamics simulations of oxidized lipid systems, with a comparison of ELBA and MARTINI force fields for coarse grained lipid …

P Siani, RM de Souza, LG Dias, R Itri… - Biochimica et Biophysica …, 2016 - Elsevier
Biological membranes and model lipid systems containing high amounts of unsaturated
lipids and sterols are subject to chemical and/or photo-induced lipid oxidation, which leads …

[HTML][HTML] Molecular simulations of the effects of phospholipid and cholesterol peroxidation on lipid membrane properties

AJP Neto, RM Cordeiro - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
Non-enzymatic lipid peroxidation may change biomembrane structure and function. Here,
we employed molecular dynamics simulations to study the effects of either phospholipid or …

[HTML][HTML] The effects of oxidised phospholipids and cholesterol on the biophysical properties of POPC bilayers

A Schumann-Gillett, ML O'Mara - Biochimica et Biophysica Acta (BBA) …, 2019 - Elsevier
Oxidation of unsaturated membrane phospholipids by oxidative stress is associated with
inflammation, infection, numerous diseases and neurodegenerative disorders. Lipid …

Molecular-scale biophysical modulation of an endothelial membrane by oxidized phospholipids

MAA Ayee, E LeMaster, TP Shentu, DK Singh… - Biophysical journal, 2017 - cell.com
The influence of two bioactive oxidized phospholipids on model bilayer properties,
membrane packing, and endothelial cell biomechanics was investigated computationally …

What does time-dependent fluorescence shift (TDFS) in biomembranes (and proteins) report on?

F Scollo, H Evci, M Amaro, P Jurkiewicz… - Frontiers in …, 2021 - frontiersin.org
The organization of biomolecules and bioassemblies is highly governed by the nature and
extent of their interactions with water. These interactions are of high intricacy and a broad …

Protective effect of cholesterol-loaded cyclodextrin pretreatment against hydrogen peroxide induced oxidative damage in ram sperm

Z Naseer, E Ahmad, M Aksoy, N Küçük, I Serin… - Cryobiology, 2015 - Elsevier
Three experiments were conducted to determine the protective effect of cholesterol-loaded
cyclodextrin (CLC) against hydrogen peroxide (H 2 O 2) or cryo-induced damage in ram …

Experimental evidence of the existence of interleaflet coupled nanodomains: an MC-FRET study

IS Vinklárek, L Vel'as, P Riegerová… - The Journal of …, 2019 - ACS Publications
Plasma membranes of living cells are compartmentalized into small submicroscopic
structures (nanodomains) having potentially relevant biological functions. Despite this …

Nonenzymatic reactions above phospholipid surfaces of biological membranes: reactivity of phospholipids and their oxidation derivatives

C Solís-Calero, J Ortega-Castro, J Frau… - … medicine and cellular …, 2015 - Wiley Online Library
Phospholipids play multiple and essential roles in cells, as components of biological
membranes. Although phospholipid bilayers provide the supporting matrix and surface for …