Amyloid formation continues to be a widely studied area because of its association with
numerous diseases, such as Alzheimer's and Parkinson's diseases. Despite a large body of …

The intercellular transfer of alpha-synuclein (α-syn) has been implicated in the progression
of Parkinson's disease (PD) and multiple system atrophy (MSA). The cellular mechanisms …

We investigated the changes in internal flexibility of amyloid-β1–40 (Aβ) fibrils grown in the
presence of rat synaptic plasma vesicles. The fibrils are produced using a modified seeded …

We compared all-atom explicit solvent molecular dynamics simulations of three types of Aβ
(1–40) fibrils: brain-seeded fibrils (2M4J, with a threefold axial symmetry) and the other two …

The interaction of biomolecules with cell membranes is crucial due to their important role in
governing the cellular function and membrane dynamics. However, most of the studies …

Alzheimer's Disease (AD) is an increasingly prevalent neurodegenerative disease.
Aggregation of Aβ peptides is important in etiology of AD. We ran all-atom, explicit water …

Актуальність теми. Дослідження молекулярних механізмів агрегації біологічних
макромолекул, зокрема, білків, є одним із фундаментальних напрямків сучасної …

Актуальність теми. Дослідження молекулярних механізмів агрегації біологічних
макромолекул, зокрема, білків, є одним із фундаментальних напрямків сучасної …