Type V secretion systems in bacteria

E Fan, N Chauhan, DG Udatha… - … of Bacterial Pathogens, 2016 - Wiley Online Library
Gram‐negative bacteria are surrounded by two membranes, called the outer and inner
membranes. The space between these membranes, the periplasm, is spanned by a …

Outer membrane protein folding from an energy landscape perspective

B Schiffrin, DJ Brockwell, SE Radford - BMC biology, 2017 - Springer
The cell envelope is essential for the survival of Gram-negative bacteria. This specialised
membrane is densely packed with outer membrane proteins (OMPs), which perform a …

Architecture and autoinhibitory mechanism of the plasma membrane Na+/H+ antiporter SOS1 in Arabidopsis

Y Wang, C Pan, Q Chen, Q **e, Y Gao, L He… - Nature …, 2023 - nature.com
Abstract Salt-overly-sensitive 1 (SOS1) is a unique electroneutral Na+/H+ antiporter at the
plasma membrane of higher plants and plays a central role in resisting salt stress. SOS1 is …

De novo design of transmembrane β barrels

AA Vorobieva, P White, B Liang, JE Horne, AK Bera… - Science, 2021 - science.org
INTRODUCTION Despite their key biological roles, only a few proteins that fold into lipid
membranes have been designed de novo. A class of membrane proteins—transmembrane …

Sculpting conducting nanopore size and shape through de novo protein design

S Berhanu, S Majumder, T Müntener, J Whitehouse… - Science, 2024 - science.org
Transmembrane β-barrels have considerable potential for a broad range of sensing
applications. Current engineering approaches for nanopore sensors are limited to naturally …

Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding

MT Doyle, JR Jimah, T Dowdy, SI Ohlemacher… - Cell, 2022 - cell.com
Transmembrane β barrel proteins are folded into the outer membrane (OM) of Gram-
negative bacteria by the β barrel assembly machinery (BAM) via a poorly understood …

BamA forms a translocation channel for polypeptide export across the bacterial outer membrane

MT Doyle, HD Bernstein - Molecular cell, 2021 - cell.com
The β-barrel assembly machine (BAM) integrates β-barrel proteins into the outer membrane
(OM) of Gram-negative bacteria. An essential BAM subunit (BamA) catalyzes integration by …

[HTML][HTML] Ecology and biogenesis of functional amyloids in Pseudomonas

SL Rouse, SJ Matthews, MS Dueholm - Journal of molecular biology, 2018 - Elsevier
Functional amyloids can be found in the extracellular matrix produced by many bacteria
during biofilm growth. They mediate the initial attachment of bacteria to surfaces and provide …

Evolution of the translocation and assembly module (TAM)

E Heinz, J Selkrig, MJ Belousoff… - Genome biology and …, 2015 - academic.oup.com
Bacterial outer membrane proteins require the beta-barrel assembly machinery (BAM) for
their correct folding and function. The central component of this machinery is BamA, an …

Transmembrane β-barrel proteins of bacteria: from structure to function

S Hermansen, D Linke, JC Leo - Advances in Protein Chemistry and …, 2022 - Elsevier
The outer membrane of Gram-negative bacteria is a specialized organelle conferring
protection to the cell against various environmental stresses and resistance to many harmful …