Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review

P Csermely, T Korcsmáros, HJM Kiss, G London… - Pharmacology & …, 2013 - Elsevier
Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

[HTML][HTML] Map** of crowdsourcing in health: systematic review

P Créquit, G Mansouri, M Benchoufi, A Vivot… - Journal of medical …, 2018 - jmir.org
Background Crowdsourcing involves obtaining ideas, needed services, or content by
soliciting Web-based contributions from a crowd. The 4 types of crowdsourced tasks …

Crowdsourcing biomedical research: leveraging communities as innovation engines

J Saez-Rodriguez, JC Costello, SH Friend… - Nature Reviews …, 2016 - nature.com
The generation of large-scale biomedical data is creating unprecedented opportunities for
basic and translational science. Typically, the data producers perform initial analyses, but it …

[PDF][PDF] Medicines in health systems: advancing access, affordability and appropriate use

M Bigdeli, DH Peters, AK Wagner… - 2014 - apps.who.int
Medicines in Health Systems Medicines in Health Systems Page 1 Edited by: Maryam Bigdeli,
David H. Peters, Anita K. Wagner Advancing access, affordability and appropriate use Medicines …

Decoding the similarities and differences among mycobacterial species

S Malhotra, SC Vedithi, TL Blundell - PLoS neglected tropical …, 2017 - journals.plos.org
Mycobacteriaceae comprises pathogenic species such as Mycobacterium tuberculosis, M.
leprae and M. abscessus, as well as non-pathogenic species, for example, M. smegmatis …

Prediction of host - pathogen protein interactions between Mycobacterium tuberculosis and Homo sapiens using sequence motifs

T Huo, W Liu, Y Guo, C Yang, J Lin, Z Rao - BMC bioinformatics, 2015 - Springer
Background Emergence of multiple drug resistant strains of M. tuberculosis (MDR-TB)
threatens to derail global efforts aimed at reigning in the pathogen. Co-infections of M …

PubChem synonym filtering process using crowdsourcing

S Kim, B Yu, Q Li, EE Bolton - Journal of Cheminformatics, 2024 - Springer
Abstract PubChem (https://pubchem. ncbi. nlm. nih. gov) is a public chemical information
resource containing more than 100 million unique chemical structures. One of the most …

Ten simple rules for cultivating open science and collaborative R&D

H Masum, A Rao, BM Good, MH Todd… - PLoS computational …, 2013 - journals.plos.org
Open science and collaborative R&D may help [1–3]. Open science has been described as
''a research accelerator''[4]. Open science implies open access [5] but goes beyond …

In silico analyses for the discovery of tuberculosis drug targets

BKS Chung, T Dick, DY Lee - Journal of Antimicrobial …, 2013 - academic.oup.com
Antibacterial drug discovery is moving from largely unproductive high-throughput screening
of isolated targets in the past decade to revisiting old, clinically validated targets and drugs …

Systems level map** of metabolic complexity in Mycobacterium tuberculosis to identify high-value drug targets

R Vashisht, AG Bhat, S Kushwaha, A Bhardwaj… - Journal of Translational …, 2014 - Springer
Background The effectiveness of current therapeutic regimens for Mycobacterium
tuberculosis (Mtb) is diminished by the need for prolonged therapy and the rise of drug …