Recently, the International Association for the Study of Pain (IASP) released clinical criteria
and a grading system for nociplastic pain affecting the musculoskeletal system. These …

Exercise is considered an important component of effective chronic pain management and it
is well-established that long-term exercise training provides pain relief. In healthy, pain-free …

Background Knee osteoarthritis is the most common joint disease and a major cause of
functional limitation and pain in adults. The aim of this literature review is to review the …

There is tremendous interpatient variability in the response to analgesic therapy (even for
efficacious treatments), which can be the source of great frustration in clinical practice. This …

Exercise and physical activity is recommended treatment for a wide range of chronic pain
conditions. In addition to several well-documented effects on physical and mental health, 8 …

Studies have suggested that quantitative sensory testing (QST) might hold a predictive value
for the development of chronic postoperative pain and the response to pharmacological …

Chronic musculoskeletal pain is linked with sensitization, and standardized methods for
assessment are needed. This study investigated (1) the test–retest reliability of computer …

Chronic pain patients often suffer from insomnia or impaired sleep which has been
associated with increased pain sensitivity, but a limited amount of studies have investigated …

Large variability in the individual response to even the most-efficacious pain treatments is
observed clinically, which has led to calls for a more personalized, tailored approach to …

Chronic postoperative pain after total knee replacement (TKR) in knee osteoarthritis (KOA)
implies clinical challenges. Widespread hyperalgesia, facilitated temporal summation of …