Non-viral vectors for RNA delivery

Y Yan, XY Liu, A Lu, XY Wang, LX Jiang… - Journal of Controlled …, 2022‏ - Elsevier
RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …

Hyaluronic acid for anticancer drug and nucleic acid delivery

F Dosio, S Arpicco, B Stella, E Fattal - Advanced drug delivery reviews, 2016‏ - Elsevier
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …

Cancer‐associated, stimuli‐driven, turn on theranostics for multimodality imaging and therapy

X Li, J Kim, J Yoon, X Chen - Advanced Materials, 2017‏ - Wiley Online Library
Advances in bioinformatics, genomics, proteomics, and metabolomics have facilitated the
development of novel anticancer agents that have decreased side effects and increased …

Biodegradable polymers for gene-delivery applications

CK Chen, PK Huang, WC Law, CH Chu… - International journal …, 2020‏ - Taylor & Francis
Gene-based therapies have emerged as a new modality for combating a myriad of currently
incurable diseases. However, the fragile nature of gene therapeutics has significantly …

A coordinative dendrimer achieves excellent efficiency in cytosolic protein and peptide delivery

L Ren, J Lv, H Wang, Y Cheng - … Chemie International Edition, 2020‏ - Wiley Online Library
Cytosolic protein delivery is a prerequisite for the development of protein therapeutics that
act on intracellular targets. Proteins are generally membrane‐impermeable and thus need a …

Anion recognition and sensing with Zn (II)–dipicolylamine complexes

HT Ngo, X Liu, KA Jolliffe - Chemical Society Reviews, 2012‏ - pubs.rsc.org
Anion recognition and sensing with Zn( ii )–dipicolylamine complexes - Chemical Society
Reviews (RSC Publishing) DOI:10.1039/C2CS35087D Royal Society of Chemistry View PDF …

Fe (III)‐Porphyrin Sonotheranostics: a Green Triple‐Regulated ROS generation nanoplatform for enhanced cancer imaging and therapy

J Zhu, C Chu, D Li, X Pang, H Zheng… - Advanced Functional …, 2019‏ - Wiley Online Library
To address the urgent need for effective sonodynamic therapy (SDT), a facile and efficient
strategy is developed for fabricating a new class of sonotheranostics. Herein, a Fe (III) …

Zinc (II)‐dipicolylamine coordination nanotheranostics: Toward synergistic nanomedicine by combined photo/gene therapy

C Chu, E Ren, Y Zhang, J Yu, H Lin, X Pang… - Angewandte …, 2019‏ - Wiley Online Library
We report the rational design of coordination‐driven self‐assembly metal–organic
nanostructures for multifunctional nanotheranostics. Zinc (II) coordination‐based nano …

Stimuli-responsive polymer–prodrug hybrid nanoplatform for multistage siRNA delivery and combination cancer therapy

PE Saw, H Yao, C Lin, W Tao, OC Farokhzad, X Xu - Nano letters, 2019‏ - ACS Publications
Nanoparticles (NPs) formulated with cationic lipids and/or polymers have shown substantial
potential for systemic delivery of RNA therapeutics such as small interfering RNA (siRNA) for …

Bioreducible zinc (II)-coordinative polyethylenimine with low molecular weight for robust gene delivery of primary and stem cells

S Liu, D Zhou, J Yang, H Zhou, J Chen… - Journal of the American …, 2017‏ - ACS Publications
To transform common low-molecular-weight (LMW) cationic polymers, such as
polyethylenimine (PEI), to highly efficient gene vectors would be of great significance but …