Understanding the factors that determine the rate at which genomes generate and fix
mutations provides important insights into key evolutionary mechanisms. We review our …

Many organisms that cause infectious diseases, particularly RNA viruses, mutate so rapidly
that their evolutionary and ecological behaviours are inextricably linked. Consequently …

RNA viruses provide unique insights into the patterns and processes of evolutionary change
in real time. The study of viral evolution is especially topical given the growing awareness …

Understanding HIV-1 transmission dynamics is relevant to both screening and intervention
strategies of HIV-1 infection. Commonly, HIV-1 transmission chains are determined based …

Abstract From June 2011 to August 2014, 21 cases of infection by severe fever with
thrombocytopenia syndrome bunyavirus (SFTSV) were confirmed in Zhoushan Islands in the …

The evolution of viral pathogens is shaped by strong selective forces that are exerted during
jumps to new hosts, confrontations with host immune responses and antiviral drugs, and …

Pathogen phylogenies are often used to infer spread among hosts. There is, however, not
an exact match between the pathogen phylogeny and the host transmission history. Here …

This review summarizes the available data on the molecular epidemiology of HIV and the
transmission of HIV drug resistance in the former USSR (FSU) in recent decades. The data …

Knowledge of HIV-1 global sequence diversity is critical for develo** an effective
prophylactic against HIV-1 infection. We developed the Hervé platform to analyze and …

Human immunodeficiency virus type 1 (HIV-1) genetic diversity, due to its high evolutionary
rate, has long been identified as a main cause of problems in the development of an efficient …