Schistosomiasis—from immunopathology to vaccines
Schistosomiasis (bilharzia) is a neglected tropical disease caused by trematode worms of
the genus Schistosoma. The transmission cycle involves human (or other mammalian) water …
the genus Schistosoma. The transmission cycle involves human (or other mammalian) water …
Immunomodulation by helminth parasites: defining mechanisms and mediators
Epidemiological and interventional human studies, as well as experiments in animal
models, strongly indicate that helminth parasitic infections can confer protection from …
models, strongly indicate that helminth parasitic infections can confer protection from …
Comparative genomics of the major parasitic worms
Nature genetics, 2019 - nature.com
Parasitic nematodes (roundworms) and platyhelminths (flatworms) cause debilitating
chronic infections of humans and animals, decimate crop production and are a major …
chronic infections of humans and animals, decimate crop production and are a major …
[HTML][HTML] Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution
Lampreys are representatives of an ancient vertebrate lineage that diverged from our own∼
500 million years ago. By virtue of this deeply shared ancestry, the sea lamprey (P. marinus) …
500 million years ago. By virtue of this deeply shared ancestry, the sea lamprey (P. marinus) …
A Systematically Improved High Quality Genome and Transcriptome of the Human Blood Fluke Schistosoma mansoni
Schistosomiasis is one of the most prevalent parasitic diseases, affecting millions of people
in develo** countries. Amongst the human-infective species, Schistosoma mansoni is also …
in develo** countries. Amongst the human-infective species, Schistosoma mansoni is also …
The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution
Abstract Background The liver fluke Fasciola hepatica is a major pathogen of livestock
worldwide, causing huge economic losses to agriculture, as well as 2.4 million human …
worldwide, causing huge economic losses to agriculture, as well as 2.4 million human …
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor
B Everts, L Hussaarts, NN Driessen… - Journal of Experimental …, 2012 - rupress.org
Omega-1, a glycosylated T2 ribonuclease (RNase) secreted by Schistosoma mansoni eggs
and abundantly present in soluble egg antigen, has recently been shown to condition …
and abundantly present in soluble egg antigen, has recently been shown to condition …
Schistosomiasis elimination: lessons from the past guide the future
Schistosomiasis is a major neglected tropical disease, with more than 200 million people
infected and close to 800 million at risk. The disease burden is estimated to exceed 70 …
infected and close to 800 million at risk. The disease burden is estimated to exceed 70 …
Genome-wide analyses reveal a role for peptide hormones in planarian germline development
Bioactive peptides (ie, neuropeptides or peptide hormones) represent the largest class of
cell-cell signaling molecules in metazoans and are potent regulators of neural and …
cell-cell signaling molecules in metazoans and are potent regulators of neural and …
The read-across hypothesis and environmental risk assessment of pharmaceuticals
Pharmaceuticals in the environment have received increased attention over the past
decade, as they are ubiquitous in rivers and waterways. Concentrations are in sub-ng to low …
decade, as they are ubiquitous in rivers and waterways. Concentrations are in sub-ng to low …