Protection against microbial infection in eukaryotes is provided by diverse cellular and
molecular mechanisms. Here, we present a comparative view of the antiviral activity of virus …

Canonical RNAi, one of the so-called RNA-silencing mechanisms, is defined as sequence-
specific RNA degradation induced by long double-stranded RNA (dsRNA). RNAi occurs in …

Mosquito-borne flaviviruses infect both mammals and mosquitoes. RNA interference (RNAi)
has been demonstrated as an anti-flavivirus mechanism in mosquitoes; however, whether …

One of the first layers of protection that metazoans put in place to defend themselves against
viruses rely on the use of proteins containing DExD/H-box helicase domains. These …

The fruitfly Drosophila melanogaster is a valuable model to unravel mechanisms of innate
immunity, in particular in the context of viral infections. RNA interference, and more …

Aging is a complex phenomenon caused by the time-dependent loss of cellular
homeodynamics and consequently of physiological organismal functions. This process is …

RNA interference (RNAi) is a conserved pathway that likely had an ancestral role in
defending genomes against selfish elements and viruses (101–103). Modern day …

RNA interference (RNAi) is a mechanism for regulating gene transcription where a small
RNA is used to repress endogenous or exogenous RNAs of interest. As such, RNAi has …