Melanins are pigment molecules that determine the skin, eye, and hair color of the human
subject to its amount, quality, and distribution. Melanocytes synthesize melanin and provide …

Controlling unwanted hyperpigmentation is a major challenge in dermatology and
cosmetology, and safe and efficacious antimelanogenic agents are deemed useful for this …

Melanogenesis is a biosynthetic pathway for the formation of the pigment melanin in human
skin. A key enzyme, tyrosinase, catalyzes the first and only rate-limiting steps in …

Cinnamic acid derivatives are widely used in cosmetics and possess various functions. This
group of compounds includes both naturally occurring and synthetic substances. On the …

Sunlight contains a significant amount of ultraviolet (UV) ray, which leads to various effects
on homeostasis in the body. Defense strategies to protect from UV rays have been …

ABSTRACT p-Coumaric acid (p-CA), also known as 4-hydroxycinnamic acid, is a phenolic
acid, which has been widely studied due to its beneficial effects against several diseases …

This study evaluated the potential of using ultra-fine grinding and electrostatic separation of
wheat bran as methods to improve the bioaccessibility of para-coumaric acid (pCA), sinapic …

Para-coumaric acid (p-CA) is a plant derived secondary metabolite belonging to the
phenolic compounds. It is widely distributed in the plant kingdom and found mainly in fruits …

Abstract Two-pore channel 2 (TPC2) resides in endolysosomal membranes but also in
lysosome-related organelles such as the melanin producing melanosomes. Gain-of-function …

Background Bioactive compounds in plant extracts are able to reduce metal ions to
nanoparticles through the process of green synthesis. Panax ginseng is an oriental …