Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

Colorectal cancer (CRC) is the most common cancer of the digestive system with high
mortality and morbidity rates. Gut microbiota is found in the intestines, especially the …

Non-alcoholic steatohepatitis (NASH) is the severe form of non-alcoholic fatty liver disease,
and is characterized by liver inflammation and fat accumulation. Dietary interventions, such …

The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …

The human gastrointestinal tract harbours an abundance of viruses, collectively known as
the gut virome. The gut virome is highly heterogeneous across populations and is linked to …

The intestinal microbiota, composed of a large population of microorganisms, is often
considered a “forgotten organ” in human health and diseases. Increasing evidence indicates …

Despite the promising advances in novel cancer therapy such as immune checkpoint
inhibitors (ICIs), limitations including therapeutic resistance and toxicity remain. In recent …

Globally, colorectal cancer (CRC) is the third most commonly diagnosed malignancy and the
second leading cause of cancer death. Arising through three major pathways, including …