Cancer stem cells (CSCs), the subpopulation of cancer cells, have the capability of
proliferation, self-renewal, and differentiation. The presence of CSCs is a key factor leading …

Prostatic diseases are very common in male dogs, accounting for 3–10% of cases submitted
to the veterinary practitioners. Commonly reported canine prostatic disorders include …

Prostate cancer (PCa) continues to rank as the second leading cause of cancer-related
mortality in western countries, despite the golden treatment using androgen deprivation …

The aberrant activation of HER2 has a pivotal role in bone metastasis implantation and
progression in several tumor types, including prostate cancer (PC). Trastuzumab and other …

Background Despite the introduction of several novel therapeutic approaches that improved
survival, metastatic castration-resistant prostate cancer (mCRPC) remains an incurable …

Prostate cancer (PCa) is the most common malignancy among men worldwide. Through
androgen receptor signaling inhibitor (ARSI) treatment, patients eventually succumb to …

Dogs are one of few species that naturally develop prostate cancer (PCa), which clinically
resembles aggressive, advanced PCa in humans. Moreover, PCa-tumor samples from dogs …

Canine mammary gland tumor (CMT) is one of the most important tumors in intact female
dogs, and due its similarity to human breast cancer (BC), it is considered a model in …

Simple Summary Mammary gland tumors are most frequent in non-castrated female dogs
and represent an interesting model for understanding tumor biology of human breast cancer …

Background Nestin has been revealed to promote tumorigenesis, progression, metastasis,
and angiogenesis of breast cancer. Although the prognostic and clinicopathological impact …