Over time, organisms have evolved strategies to cope with the abundance of dioxygen on
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …

Covering: 2014. Previous review: Nat. Prod. Rep., 2015, 32, 116–211 This review covers the
literature published in 2014 for marine natural products (MNPs), with 1116 citations (753 for …

Enzyme function annotation is a fundamental challenge, and numerous computational tools
have been developed. However, most of these tools cannot accurately predict functional …

Although flavin-dependent halogenases (FDHs) are attractive for C–H bond activation, their
applications are limited due to low turnover and stability. We have previously shown that …

Naturally produced halogenated compounds are ubiquitous across all domains of life where
they perform a multitude of biological functions and adopt a diversity of chemical structures …

Nature has evolved halogenase enzymes to regioselectively halogenate a diverse range of
biosynthetic precursors, with the halogens introduced often having a profound effect on the …

Flavoprotein monooxygenases (FPMOs) are single-or two-component enzymes that
catalyze a diverse set of chemo-, regio-and enantioselective oxyfunctionalization reactions …

The enzymatic generation of carbon–halogen bonds is a powerful strategy used by both
nature and synthetic chemists to tune the bioactivity, bioavailability and reactivity of …

In numerous food businesses, natural pigments are frequently utilized as food colorants.
Colorants give nutritional value to food items in addition to improving its appeal …

Suzuki‐Miyaura Coupling Reaction (SMCR) has been extensively used in the total synthesis
of natural products. We underscored these achievements in a report published in …