Therapeutic plasticity of neural stem cells
L Ottoboni, B von Wunster, G Martino - Frontiers in neurology, 2020 - frontiersin.org
Neural stem cells (NSCs) have garnered significant scientific and commercial interest in the
last 15 years. Given their plasticity, defined as the ability to develop into different phenotypes …
last 15 years. Given their plasticity, defined as the ability to develop into different phenotypes …
From single cells to tissue self‐organization
AXS Dos Santos, P Liberali - The FEBS journal, 2018 - pmc.ncbi.nlm.nih.gov
Self‐organization is a process by which interacting cells organize and arrange themselves
in higher order structures and patterns. To achieve this, cells must have molecular …
in higher order structures and patterns. To achieve this, cells must have molecular …
Kaempferol ameliorates the inhibitory activity of dexamethasone in the osteogenesis of MC3T3-E1 cells by JNK and p38-MAPK pathways
B **e, Z Zeng, S Liao, C Zhou, L Wu… - Frontiers in pharmacology, 2021 - frontiersin.org
Kaempferol has been reported to exhibit beneficial effect on the osteogenic differentiation in
mesenchymal stem cells (MSC) and osteoblasts. In our previous study, dexamethasone …
mesenchymal stem cells (MSC) and osteoblasts. In our previous study, dexamethasone …
[HTML][HTML] Palbociclib releases the latent differentiation capacity of neuroblastoma cells
KM Ferguson, SL Gillen, L Chaytor, E Poon… - Developmental Cell, 2023 - cell.com
Neuroblastoma is the most common extracranial solid tumor in infants, arising from
developmentally stalled neural crest-derived cells. Driving tumor differentiation is a …
developmentally stalled neural crest-derived cells. Driving tumor differentiation is a …
Chromatin accessibility dynamics and single cell RNA-Seq reveal new regulators of regeneration in neural progenitors
Vertebrate appendage regeneration requires precisely coordinated remodeling of the
transcriptional landscape to enable the growth and differentiation of new tissue, a process …
transcriptional landscape to enable the growth and differentiation of new tissue, a process …
Phospho-regulation of ATOH1 is required for plasticity of secretory progenitors and tissue regeneration
The intestinal epithelium is largely maintained by self-renewing stem cells but with
apparently committed progenitors also contributing, particularly following tissue damage …
apparently committed progenitors also contributing, particularly following tissue damage …
Resveratrol mediated regulation of hippocampal neuroregenerative plasticity via SIRT1 pathway in synergy with Wnt signaling: Neurotherapeutic implications to …
K Surya, N Manickam… - Journal of …, 2023 - content.iospress.com
Alzheimer's disease (AD) is a major form of dementia. Abnormal amyloidogenic event-
mediated degeneration of cholinergic neurons in the cognitive centers of the brain has been …
mediated degeneration of cholinergic neurons in the cognitive centers of the brain has been …
Translating neural stem cells to neurons in the mammalian brain
The mammalian neocortex underlies our perception of sensory information, performance of
motor activities, and higher-order cognition. During mammalian embryogenesis, radial glial …
motor activities, and higher-order cognition. During mammalian embryogenesis, radial glial …
The cellular and molecular basis of cnidarian neurogenesis
F Rentzsch, M Layden, M Manuel - Wiley Interdisciplinary …, 2017 - Wiley Online Library
Neurogenesis initiates during early development and it continues through later
developmental stages and in adult animals to enable expansion, remodeling, and …
developmental stages and in adult animals to enable expansion, remodeling, and …
Phosphatidylcholine restores neuronal plasticity of neural stem cells under inflammatory stress
D Magaquian, S Delgado Ocaña, C Perez… - Scientific reports, 2021 - nature.com
The balances between NSCs growth and differentiation, and between glial and neuronal
differentiation play a key role in brain regeneration after any pathological conditions. It is …
differentiation play a key role in brain regeneration after any pathological conditions. It is …