Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …

One of the leading causes of morbidity and premature mortality in older people is frailty.
Frailty occurs when multiple physiological systems decline, to the extent that an individual's …

Background. Patients on kidney replacement therapy comprise a vulnerable population and
may be at increased risk of death from coronavirus disease 2019 (COVID-19). Currently …

The efficacy of exercise to reverse frailty in the aging population has not been extensively
investigated. This study aimed to investigate the effectiveness of a multicomponent exercise …

Background Guidelines recommend routine frailty screening for all hospitalised older adults
to inform care decisions, based mainly on studies in elective or speciality-specific settings …

Background The ability of acute care providers to cope with the influx of frail older patients is
increasingly stressed, and changes need to be made to improve care provided to older …

Background Frail older adults experience higher rates of adverse health outcomes.
Therefore, assessing pre-hospital frailty early in the course of care is essential to identify the …

Background Frailty is a common and clinically significant condition among geriatric
populations. Although well-evidenced pooled estimates of the prevalence of frailty exist …

Police use of force is at the forefront of public awareness in many countries. Body-worn
videos (BWVs) have been proposed as a new way of reducing police use of force, as well as …

The human gut microbiome is a collection of bacteria, protozoa, fungi, and viruses that
coexist in our bodies and are essential in protective, metabolic, and physiologic functions of …