As an essential micronutrient, manganese (Mn) participates in various physiological
processes and plays important roles in host immune system, hematopoiesis, endocrine …

Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

The immunologically “cold” microenvironment of triple negative breast cancer results in
resistance to current immunotherapy. Here, we reveal the immunoadjuvant property of gas …

An immunosuppressive tumour microenvironment is a major obstacle in the control of
pancreatic and other solid cancers,–. Agonists of the stimulator of interferon g enes (STING) …

Oncolytic bacteria can trigger innate immune activity. However, the antitumour efficacy of
inactivated bacteria is poor, and attenuated live bacteria pose substantial safety risks. Here …

Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune
responses of the body. It has become another important modality of anti-tumor therapy with …

Immunotherapy is currently the most promising treatment strategy for long-term tumor
regression. However, current cancer immunotherapy shows low response rates due to …

The immunosuppressive tumor microenvironment (TME) is a huge hurdle in immunotherapy.
Sono‐immunotherapy is a new treatment modality that can reverse immunosuppressive …

The clinical utility of stimulator of interferon genes (STING) agonists has been limited due to
poor tumour-targeting and unwanted toxicity following systemic delivery. Here we describe a …

Lack of sufficient cytotoxic T lymphocytes (CD8+ T cells) infiltration and dysfunctional state of
CD8+ T cells are considered enormous obstacles to antitumor immunity. Herein, we …